Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574) Polyclonal Antibody | Invitrogen 44-1000G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574) Polyclonal Antibody

catalog :

44-1000G

quantity :

100 uL

price :

US 520.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 3

Reference
Lv F, Li X, Wang Y. Lycorine inhibits angiogenesis by docking to PDGFRα. BMC Cancer. 2022;22:873 pubmed publisher
Kikuchi A, Singh S, Poddar M, Nakao T, Schmidt H, Gayden J, et al. Hepatic Stellate Cell-Specific Platelet-Derived Growth Factor Receptor-α Loss Reduces Fibrosis and Promotes Repair after Hepatocellular Injury. Am J Pathol. 2020;190:2080-2094 pubmed publisher
Kikuchi A, Pradhan Sundd T, Singh S, Nagarajan S, Loizos N, Monga S. Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration. Am J Pathol. 2017;187:2273-2287 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574) Polyclonal Antibody

Catalog # :

44-1000G

Quantity :

100 uL

Price :

US 520.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Immunogen :

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human PDGFRA that contains tyrosines 572 and 574 and PDGFRB tyrosines 579 and 581. The sequence is conserved in PDGFRA mouse, rat and frog.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000

Aliases :

AI115593; AI528809; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140 antigen-like family member B; CD140a; CD140a antigen; CD140b; GAS9; IBGC4; IMF1; JTK12; KOGS; MGC74795; PDGF alpha chain; PDGF beta chain; PDGF Receptor alpha; PDGFACE; PDGFR; PDGFR1; PDGFR-1; PDGFR2; PDGFR-2; Pdgfra; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; Pdgfrb; PDGF-R-beta; PDGFR-beta; PENTT; PGFRB; platelet derived growth factor receptor alpha; platelet derived growth factor receptor beta; platelet derived growth factor receptor, alpha polypeptide; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 1; platelet-derived growth factor receptor 2; Platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; platelet-derived growth factor receptor, alpha polypeptide; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA