RXRA Monoclonal Antibody (K8508) | Invitrogen 433900 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RXRA Monoclonal Antibody (K8508)

catalog :

433900

quantity :

100 uL

price :

US 552.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K8508

The same clone is also sold as:

R&D Systems: PP-K8508-00

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 2

Reference
Li Y, Zhu Y, Feng S, Ishida Y, Chiu T, Saito T, et al. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep. 2022;38:110284 pubmed publisher
Su G, Wang W, Zhao X, Chen J, Zheng J, Liu M, et al. Enhancer architecture-dependent multilayered transcriptional regulation orchestrates RA signaling-induced early lineage differentiation of ESCs. Nucleic Acids Res. 2021;49:11575-11595 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RXRA Monoclonal Antibody (K8508)

Catalog # :

433900

Quantity :

100 uL

Price :

US 552.00

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ChIP Assay: Assay-dependent, ELISA: 0.1 ug/mL, Gel Shift: Assay-dependent, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 3-20 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 ug/mL

Species :

Human, Mouse, Rat

Clone :

K8508

Isotype :

IgG2a

Storage :

Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C

Description :

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Immunogen :

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RXR--alpha (2-133 aa).

Format :

Liquid

Applications w/Dilutions :

Aliases :

9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1