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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ATP5A1 Monoclonal Antibody (15H4C4)
catalog :
43-9800
quantity :
100 µg
price :
US 455.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
15H4C4
reactivity :
human, mouse, rat, bovine, fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Winter L, Türk M, Harter P, Mittelbronn M, Kornblum C, Norwood F, et al. Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy. Acta Neuropathol Commun. 2016;4:44 pubmed publisher
  • western blot; fruit fly ; 1:5000; fig 4
Vagnoni A, Hoffmann P, Bullock S. Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons. J Cell Sci. 2016;129:178-90 pubmed publisher
  • western blot; rat; fig 9
Dun Y, Vargas J, Brot N, Finnemann S. Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells. Free Radic Biol Med. 2013;65:1340-1351 pubmed publisher
Zhang Y, Szramowski M, Sun S, Henderson G. Combining albumin deficiency and acute exercise reduces hepatic lipid droplet size in mice. Lipids Health Dis. 2023;22:78 pubmed publisher
Acin Perez R, Beninc xe1 C, Fernández Del Río L, Shu C, Baghdasarian S, Zanette V, et al. Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies. EMBO J. 2023;42:e111699 pubmed publisher
Liu P, Chang K, Requejo G, Bai H. mTORC2 protects the heart from high-fat diet-induced cardiomyopathy through mitochondrial fission in Drosophila. Front Cell Dev Biol. 2022;10:866210 pubmed publisher
Meseguer S, Rubio M. mt tRFs, New Players in MELAS Disease. Front Physiol. 2022;13:800171 pubmed publisher
Tian D, Han M. Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists. Dev Cell. 2022;57:361-372.e5 pubmed publisher
Deutschman E, Ward J, Kumar A, Ray G, Welch N, Lemieux M, et al. Condensin II protein dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responses. J Cell Sci. 2019;132: pubmed publisher
Ait Aissa K, Blaszak S, Beutner G, Tsaih S, Morgan G, Santos J, et al. Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease. Sci Rep. 2019;9:7623 pubmed publisher
Nilangekar K, Murmu N, Sahu G, Shravage B. Generation and Characterization of Germline-Specific Autophagy and Mitochondrial Reactive Oxygen Species Reporters in Drosophila. Front Cell Dev Biol. 2019;7:47 pubmed publisher
Bonora M, Ito K, Morganti C, Pinton P, Ito K. Membrane-potential compensation reveals mitochondrial volume expansion during HSC commitment. Exp Hematol. 2018;68:30-37.e1 pubmed publisher
Qi B, Han M. Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase. Cell. 2018;175:571-582.e11 pubmed publisher
Bryant D, Liu Y, Datta S, Hariri H, Seda M, Anderson G, et al. SNX14 mutations affect endoplasmic reticulum-associated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20. Hum Mol Genet. 2018;27:1927-1940 pubmed publisher
Dodson M, Wani W, Redmann M, Benavides G, Johnson M, Ouyang X, et al. Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons. Autophagy. 2017;13:1828-1840 pubmed publisher
Song S, Kole S, Bernier M. A chemical cross-linking method for the analysis of binding partners of heat shock protein-90 in intact cells. Biotechniques. 2012;:1-7 pubmed publisher
product information
Product Type :
Antibody
Product Name :
ATP5A1 Monoclonal Antibody (15H4C4)
Catalog # :
43-9800
Quantity :
100 µg
Price :
US 455.00
Clonality :
Monoclonal
Purity :
IgG fraction
Host :
Mouse
Reactivity :
Bovine, Drosophila, Human, Mouse, Rat
Applications :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: 1-2 µg/mL, Immunohistochemistry: 1 µg/mL, Western Blot: 1.0 µg/mL
Species :
Bovine, Drosophila, Human, Mouse, Rat
Clone :
15H4C4
Isotype :
IgG2b, kappa
Storage :
4° C
Description :
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16.
Immunogen :
Bovine Complex V
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/mL, Immunocytochemistry: 1-2 µg/mL, Immunohistochemistry: 1 µg/mL, Western Blot: 1.0 µg/mL
Aliases :
AI035633; AL022851; AL023067; alpha subunit ATP synthase isoform precursor (EC 3.6.1.34); ATP synthase alpha chain, mitochondrial; ATP synthase alpha subunit; ATP synthase alpha subunit precursor; ATP synthase F1 subunit alpha; ATP synthase subunit alpha heart isoform, mitochondrial; ATP synthase subunit alpha liver isoform, mitochondrial; ATP synthase subunit alpha, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2; ATP sythase (F1-ATPase) alpha subunit; ATP5A; Atp5a1; ATP5A2; ATP5AL2; ATP5F1A; atp5fa1; ATPM; cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1; COXPD22; D18Ertd206e; EGK_09658; epididymis secretory sperm binding protein Li 123m; hATP1; HEL-S-123m; iso; MC5DN4; mitochondrial ATP synthase alpha chain; mitochondrial ATP synthase alpha subunit; mitochondrial ATP synthetase, oligomycin-resistant; mitochondrial H+-ATP synthase alpha subunit; modifier of Min 2; Mom2; OMR; ORM; zgc:154103
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA