PP1 alpha Monoclonal Antibody (10C6-3) | Invitrogen 43-8100 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PP1 alpha Monoclonal Antibody (10C6-3)

catalog :

43-8100

quantity :

100 µg

price :

US 500

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10C6-3

reactivity :

human, mouse, rat, dogs

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; fig 1 western blot; human; fig 1	Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher
western blot; human	Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed publisher
	Grimm P, Tatomir A, Rosenbaek L, Kim B, Li D, Delpire E, et al. Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure. J Clin Invest. 2023;133: pubmed publisher
	Kasikara C, Schilperoort M, Gerlach B, Xue C, Wang X, Zheng Z, et al. Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis. J Clin Invest. 2021;131: pubmed publisher
	Dingar D, Tu W, Resetca D, Lourenco C, Tamachi A, De Melo J, et al. MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability. Nat Commun. 2018;9:3502 pubmed publisher
	Partida G, Fasoli A, Fogli Iseppe A, Ogata G, Johnson J, Thambiaiyah V, et al. Autophosphorylated CaMKII Facilitates Spike Propagation in Rat Optic Nerve. J Neurosci. 2018;38:8087-8105 pubmed publisher
	Chen M, Wan L, Zhang J, Zhang J, Méndez L, Clohessy J, et al. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nat Commun. 2018;9:159 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PP1 alpha Monoclonal Antibody (10C6-3)

Catalog # :

43-8100

Quantity :

100 µg

Price :

US 500

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Canine, Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Species :

Canine, Human, Mouse, Non-human primate, Rat

Clone :

10C6-3

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen :

Mixture of two peptides from the C-terminal regions of human PP1 alpha protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Aliases :

96A; CG6593; CG6593-PA; CG6593-PB; dism2; Dmel CG6593; Dmel_CG6593; DmPp1-96A; GADD34; LD14639p; MGC15877; MGC1674; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1A; PP-1A; PP1A-96A; PP1alpha; PP1alpha[[1]]; PP1alpha96A; pp1alpha-96A; Pp1alpha-96A-PA; Pp1alpha-96A-PB; PP1c; PP1c 96A; PPP1A; Ppp1c; Ppp1ca; protein phosphatase 1; protein phosphatase 1 catalytic subunit alpha; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase 1alpha at 96A; protein phosphatase type 1 alpha catalytic subunit; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase alpha-1 isoform; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155

more info or order :

Invitrogen product webpage