PAX6 Polyclonal Antibody | Invitrogen 42-6600 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PAX6 Polyclonal Antibody

catalog :

42-6600

quantity :

100 µg

price :

US 500.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 24

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; 1:200; fig s2c	Nuber S, Chung C, Tardiff D, Bechade P, McCaffery T, Shimanaka K, et al. A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity. Neurotherapeutics. 2022;19:1018-1036 pubmed publisher
immunohistochemistry; mouse; 1:300; loading ...; tbl 1	Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher
immunocytochemistry; human; 1:1000; fig s1 western blot; human; 1:1000	Fang D, Yan S, Yu Q, Chen D, Yan S. Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons. Sci Rep. 2016;6:31462 pubmed publisher
	Zushin P, Zhou Y, Li A, Ashley E, Wheeler M, Wu J. Generation of two human iPSC lines with Exon 3 mutations in BCL2-Associated Athanogene 3 (BAG3) from dilated cardiomyopathy patients. Stem Cell Res. 2023;67:103019 pubmed publisher
	An N, Zhang J, Mo F, Luan X, Tian L, Shen Q, et al. De novo genes with an lncRNA origin encode unique human brain developmental functionality. Nat Ecol Evol. 2023;7:264-278 pubmed publisher
	Jimenez Tellez N, Vera C, Yıldırım Z, Vicente Guevara J, Zhang T, Wu J. Generation of two iPSC lines from long QT syndrome patients carrying SNTA1 variants. Stem Cell Res. 2023;66:103003 pubmed publisher
	Yıldırım Z, Kojic A, Yan C, Wu M, Vagelos R, Wu J. Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients caused by heterozygous mutations in the HCN4 gene. Stem Cell Res. 2022;65:102951 pubmed publisher
	Alonzo M, Contreras J, Ye S, Lin H, Hernandez Rosario L, McBride K, et al. Characterization of an iPSC line NCHi006-A from a patient with hypoplastic left heart syndrome (HLHS). Stem Cell Res. 2022;64:102892 pubmed publisher
	Br xe1 s J, Henriques D, Moreira R, Santana M, Silva Pedrosa R, Ad xe3 o D, et al. Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases. Sci Rep. 2022;12:12513 pubmed publisher
	Caudal A, Mondejar Parre xf1 o G, Vera C, Williams D, Shenoy S, Liang D, et al. Generation of human induced pluripotent stem cell lines carrying heterozygous PLN mutation from dilated cardiomyopathy patients. Stem Cell Res. 2022;63:102855 pubmed publisher
	Gajewska K, Haynes J, Jans D. Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation. Cells. 2022;11: pubmed publisher
	Jahagirdar D, Yadav S, Gore M, Korpale V, Mathpati C, Chidambaram S, et al. Compartmentalized microfluidic device for in vitro co-culture of retinal cells. Biotechnol J. 2022;17:e2100530 pubmed publisher
	Guo L, Bian J, Davis A, Liu P, Kempton H, Zhang X, et al. Multiplexed genome regulation in vivo with hyper-efficient Cas12a. Nat Cell Biol. 2022;24:590-600 pubmed publisher
	Manhas A, Jahng J, Vera C, Shenoy S, Knowles J, Wu J. Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants. Stem Cell Res. 2022;61:102774 pubmed publisher
	Lin C, Sun Y, Chan C, Wu M, Gu L, Davis A, et al. Identification of cis-regulatory modules for adeno-associated virus-based cell-type-specific targeting in the retina and brain. J Biol Chem. 2022;298:101674 pubmed publisher
	Guo Y, Wu J, Wang M, Wang X, Jian Y, Yang C, et al. The Metabolite Saccharopine Impairs Neuronal Development by Inhibiting the Neurotrophic Function of Glucose-6-Phosphate Isomerase. J Neurosci. 2022;42:2631-2646 pubmed publisher
	Cai M, Chai S, Xiong T, Wei J, Mao W, Zhu Y, et al. Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease. Front Cell Dev Biol. 2021;9:695007 pubmed publisher
	Baines K, Hillier D, Haddad F, Rajakumar N, Schmid S, Renaud S. Maternal Immune Activation Alters Fetal Brain Development and Enhances Proliferation of Neural Precursor Cells in Rats. Front Immunol. 2020;11:1145 pubmed publisher
	Goto Silva L, Ayad N, Herzog I, Silva N, Lamien B, Orlande H, et al. Computational fluid dynamic analysis of physical forces playing a role in brain organoid cultures in two different multiplex platforms. BMC Dev Biol. 2019;19:3 pubmed publisher
	Yu X, Qiu W, Yang L, Zhang Y, He M, Li L, et al. Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution. EMBO J. 2019;38: pubmed publisher
	Li T, Zheng Y, Li Y, Ye D. Comparison of in vitro Neuronal Differentiation Capacity Between Mouse Epiblast Stem Cells Derived From Nuclear Transfer and Naturally Fertilized Embryos. Front Mol Neurosci. 2018;11:392 pubmed publisher
	Mo J, Liu Q, Kou Z, Wu K, Yang P, Chen X, et al. MicroRNA-365 modulates astrocyte conversion into neuron in adult rat brain after stroke by targeting Pax6. Glia. 2018;66:1346-1362 pubmed publisher
	Steens J, Zuk M, Benchellal M, Bornemann L, Teichweyde N, Hess J, et al. In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells. Stem Cell Reports. 2017;8:919-932 pubmed publisher
	Fang D, Qing Y, Yan S, Chen D, Yan S. Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs. Stem Cell Reports. 2016;7:678-692 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PAX6 Polyclonal Antibody

Catalog # :

42-6600

Quantity :

100 µg

Price :

US 500.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1:100, Immunocytochemistry: 2-3 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1-2 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.

Immunogen :

Human Pax6

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:100, Immunocytochemistry: 2-3 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1-2 µg/mL

Aliases :

1500038E17Rik; AEY11; AN; AN2; Aniridia; aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; paired box protein Pax-6; Pax6; Pax-6; PAX6 protein; Sey; small eye; transcription factor; WAGR

more info or order :

Invitrogen product webpage