This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TBX5 Polyclonal Antibody
catalog :
42-6500
quantity :
100 ug
price :
US 451.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 5
Reference
Dai Y, Nasehi F, Winchester C, Foley A. Tbx5 overexpression in embryoid bodies increases TAK1 expression but does not enhance the differentiation of sinoatrial node cardiomyocytes. Biol Open. 2023;12: pubmed publisher
Dark N, Cosson M, Tsansizi L, Owen T, Ferraro E, Francis A, et al. Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells. Cell Rep Methods. 2023;3:100456 pubmed publisher
Zhao H, Zhang Y, Xu X, Sun Q, Yang C, Wang H, et al. Sall4 and Myocd Empower Direct Cardiac Reprogramming From Adult Cardiac Fibroblasts After Injury. Front Cell Dev Biol. 2021;9:608367 pubmed publisher
Li W, Li B, Li T, Zhang E, Wang Q, Chen S, et al. Identification and analysis of KLF13 variants in patients with congenital heart disease. BMC Med Genet. 2020;21:78 pubmed publisher
Jeong H, Jung E, Sim Y, Kim S, Jang J, Hong K, et al. Fbxo25 controls Tbx5 and Nkx2-5 transcriptional activity to regulate cardiomyocyte development. Biochim Biophys Acta. 2015;1849:709-21 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TBX5 Polyclonal Antibody
Catalog # :
42-6500
Quantity :
100 ug
Price :
US 451.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 2 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C
Description :
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
Immunogen :
Synthetic peptide derived from an internal region of the human, predicted dog, and predicted chimpanzee Tbx5 proteins, which differ from mouse and rat by one conservative amino acid change
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
HOS; T-box 5; T-box protein 5; T-box transcription factor TBX5; TBX5
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA