NDRG1 Polyclonal Antibody | Invitrogen 42-6200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NDRG1 Polyclonal Antibody

catalog :

42-6200

quantity :

100 µg

price :

US 506.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 2	Lee J, Chiang K, Feng T, Chen Y, Chuang S, Tsui K, et al. The Iron Chelator, Dp44mT, Effectively Inhibits Human Oral Squamous Cell Carcinoma Cell Growth in Vitro and in Vivo. Int J Mol Sci. 2016;17: pubmed publisher
western blot; human; fig 3	Tsui K, Lin Y, Chung L, Chuang S, Feng T, Chiang K, et al. Prostate-derived ets factor represses tumorigenesis and modulates epithelial-to-mesenchymal transition in bladder carcinoma cells. Cancer Lett. 2016;375:142-151 pubmed publisher
	Tsui K, Chang K, Sung H, Hsu S, Lin Y, Hou C, et al. Mucosa-Associated Lymphoid Tissue 1 Is an Oncogene Inducing Cell Proliferation, Invasion, and Tumor Growth via the Upregulation of NF-κB Activity in Human Prostate Carcinoma Cells. Biomedicines. 2021;9: pubmed publisher
	Tsui K, Hsu S, Chung L, Lin Y, Feng T, Lee T, et al. Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells. Sci Rep. 2015;5:12870 pubmed publisher
	Chen B, Zaveri P, Longtine M, Nelson D. N-myc downstream-regulated gene 1 (NDRG1) mediates pomegranate juice protection from apoptosis in hypoxic BeWo cells but not in primary human trophoblasts. Placenta. 2015;36:847-53 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NDRG1 Polyclonal Antibody

Catalog # :

42-6200

Quantity :

100 µg

Price :

US 506.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: 5 µg, Western Blot: 1-3 µg/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20°C

Description :

NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation. Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D) that is characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes and hollow feet. NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon and the cells that border the lumen.

Immunogen :

Synthetic peptide derived from the N-terminal region of the human and predicted chimpanzee CAP43 proteins, which differs from predicted bovine by one amino acid change and from mouse and rat by two amino acid changes

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: 5 µg, Western Blot: 1-3 µg/mL

Aliases :

CAP43; CMT4D; differentiation-related gene 1 protein; DRG1; DRG-1; GC4; HMSNL; Ndr1; Ndrg1; Ndrl; nickel-specific induction protein Cap43; NMSL; N-myc downstream regulated 1; N-myc downstream regulated gene 1; N-myc downstream-regulated gene 1 protein; Protein Ndr1; protein NDRG1; protein regulated by oxygen-1; PROXY1; Reducing agents and tunicamycin-responsive protein; Rit42; RTP; TARG1; TDD5