Raptor Polyclonal Antibody | Invitrogen 42-4000 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Raptor Polyclonal Antibody

catalog :

42-4000

quantity :

100 µg

price :

US 500.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 5a	Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed publisher
western blot; human; loading ...; fig s3d	Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
	Jiang W, Sun M, Wang Y, Zheng M, Yuan Z, Mai S, et al. Critical Role of Notch-1 in Mechanistic Target of Rapamycin Hyperactivity and Vascular Inflammation in Patients With Takayasu Arteritis. Arthritis Rheumatol. 2022;74:1235-1244 pubmed publisher
	Engmann A, Hatch J, Nanda P, Veeraraghavan P, Ozkan A, Poulopoulos A, et al. Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. Nat Protoc. 2022;17:222-251 pubmed publisher
	Drizyte Miller K, Chen J, Cao H, Schott M, McNiven M. The small GTPase Rab32 resides on lysosomes to regulate mTORC1 signaling. J Cell Sci. 2020;133: pubmed publisher
	Zhang J, Zhao L, Wang J, Cheng Z, Sun M, Zhao J, et al. Targeting Mechanistic Target of Rapamycin Complex 1 Restricts Proinflammatory T Cell Differentiation and Ameliorates Takayasu Arteritis. Arthritis Rheumatol. 2020;72:303-315 pubmed publisher
	Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Raptor Polyclonal Antibody

Catalog # :

42-4000

Quantity :

100 µg

Price :

US 500.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 0.25 µg/ml

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human, mouse, and predicted rat raptor proteins

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 0.25 µg/ml

Aliases :

4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Rap; RAPTOR; regulatory associated protein of MTOR complex 1; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RGD1311784; RPTOR

more info or order :

Invitrogen product webpage