SMAD7 Polyclonal Antibody | Invitrogen 42-0400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SMAD7 Polyclonal Antibody

catalog :

42-0400

quantity :

100 µg

price :

US 560.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1a, 1d	Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed publisher
	Li J, Li R, Tuleta I, Hernandez S, Humeres C, Hanna A, et al. The role of endogenous Smad7 in regulating macrophage phenotype following myocardial infarction. FASEB J. 2022;36:e22400 pubmed publisher
	Maldotti M, Lauria A, Anselmi F, Molineris I, Tamburrini A, Meng G, et al. The acetyltransferase p300 is recruited in trans to multiple enhancer sites by lncSmad7. Nucleic Acids Res. 2022;50:2587-2602 pubmed publisher
	Kim I, Lee M, Park M, Seong E, Lee D, Lee S, et al. Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction. Biomed Res Int. 2020;2020:6143542 pubmed publisher
	Ren Y, Jian X, Zhang Z, Ning Q, Kan B, Kong L. Effects of tacrolimus on the TGF‑β1/SMAD signaling pathway in paraquat‑exposed rat alveolar type II epithelial cells. Mol Med Rep. 2020;22:3687-3694 pubmed publisher
	Ghiroldi A, Piccoli M, Creo P, Cirillo F, Rota P, D Imperio S, et al. Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation. Biochem J. 2020;477:3401-3415 pubmed publisher
	Cho C, Mukherjee R, Peck A, Sun Y, McBrearty N, Katlinski K, et al. Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis. Oncogene. 2020;39:6129-6137 pubmed publisher
	Ji T, Feng W, Zhang X, Zang K, Zhu X, Shang F. HDAC inhibitors promote pancreatic stellate cell apoptosis and relieve pancreatic fibrosis by upregulating miR-15/16 in chronic pancreatitis. Hum Cell. 2020;33:1006-1016 pubmed publisher
	Ji Q, Qi D, Xu X, Xu Y, Goodman S, Kang L, et al. Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis. Mol Ther Nucleic Acids. 2018;11:170-179 pubmed publisher
	Lim R, Barker G, Lappas M. SMAD7 regulates proinflammatory and prolabor mediators in amnion and myometrium. Biol Reprod. 2017;97:288-301 pubmed publisher
	Jeong M, Kim S, Kang H, Park K, Park W, Yang S, et al. Cucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF- Î²/Smads Signalings. PLoS ONE. 2015;10:e0136236 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SMAD7 Polyclonal Antibody

Catalog # :

42-0400

Quantity :

100 µg

Price :

US 560.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1-2 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8 and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human SMAD7

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1-2 µg/mL

Aliases :

CRCS3; FLJ16482; hSMAD7; MAD (mothers against decapentaplegic, Drosophila) homolog 7; MAD homolog 7; MAD homolog 8; MADH7; MADH8; mothers against decapentaplegic homolog 7; Mothers against decapentaplegic homolog 8; Mothers against decapentaplegic, drosophila, homolog of, 7; mothers against decapentaplegic-like protein 7; mothers against DPP 7; mothers against DPP homolog 7; mothers against DPP homolog 8; SMAD; SMAD 7; SMAD family member 7; SMAD, mothers against DPP homolog 7; Smad7

more info or order :

Invitrogen product webpage