LXR beta Monoclonal Antibody (K8917) | Invitrogen 418400 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LXR beta Monoclonal Antibody (K8917)

catalog :

418400

quantity :

100 uL

price :

US 622.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K8917

The same clone is also sold as:

R&D Systems: PP-K8917-00

reactivity :

human

application :

western blot, ELISA, immunoprecipitation

citations: 1

Reference
Courtaut F, Derangère V, Chevriaux A, Ladoire S, Cotte A, Arnould L, et al. Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization. Oncotarget. 2015;6:26651-62 pubmed publisher

product information

Product Type :

Antibody

Product Name :

LXR beta Monoclonal Antibody (K8917)

Catalog # :

418400

Quantity :

100 uL

Price :

US 622.00

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 0.1 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 ug/mL

Species :

Human

Clone :

K8917

Isotype :

IgG2a

Storage :

Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C

Description :

The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

Immunogen :

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human LXR-beta (2-86 aa).

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 ug/mL

Aliases :

AI194859; liver X nuclear receptor beta; liver X receptor beta; LX receptor beta; LXR; LXR beta; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; Nr1h2; NR1H2 protein; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 2; UNR; Unr2; UR