This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LXR alpha Monoclonal Antibody (PPZ0412)
catalog :
418300
quantity :
100 uL
price :
US 484.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PPZ0412

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
LXR alpha Monoclonal Antibody (PPZ0412)
Catalog # :
418300
Quantity :
100 uL
Price :
US 484.00
Clonality :
Monoclonal
Purity :
Ammonium sulfate precipitation
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
ChIP Assay: Assay-dependent, ELISA: 0.2 ug/mL, Gel Shift: Assay-dependent, Immunohistochemistry (Paraffin): 3-20 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL
Species :
Human, Mouse, Rat
Clone :
PPZ0412
Isotype :
IgG2a
Storage :
Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C
Description :
NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activation activity. Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides. NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8. It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.
Immunogen :
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with E.coli-expressed recombinant human LXR-alpha (164-447 aa).
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: Assay-dependent, ELISA: 0.2 ug/mL, Gel Shift: Assay-dependent, Immunohistochemistry (Paraffin): 3-20 ug/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL
Aliases :
AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA