LXR alpha Monoclonal Antibody (K8607) | Invitrogen 418200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

LXR alpha Monoclonal Antibody (K8607)

catalog :

418200

quantity :

100 uL

price :

US 562.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K8607

The same clone is also sold as:

R&D Systems: PP-K8607-00

reactivity :

human

application :

western blot, ELISA, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

LXR alpha Monoclonal Antibody (K8607)

Catalog # :

418200

Quantity :

100 uL

Price :

US 562.00

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human

Applications :

ChIP Assay: Assay-dependent, ELISA: 0.3 ug/mL, Gel Shift: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 2 ug/mL

Species :

Human

Clone :

K8607

Isotype :

IgG2a

Storage :

Maintain refrigerated at 2-8 C for up to 1 month. For long term storage store at -20 C

Description :

NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activation activity. Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides. NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8. It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.

Immunogen :

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human LXR--alpha (2-97 aa).

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: Assay-dependent, ELISA: 0.3 ug/mL, Gel Shift: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 2 ug/mL

Aliases :

AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1