This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HNF4A Monoclonal Antibody (H1415)
catalog :
417700
quantity :
100 µg
price :
US 449.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H1415
reactivity :
African green monkey, human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Burdin D, Kolobov A, Brocker C, Soshnev A, Samusik N, Demyanov A, et al. Diabetes-linked transcription factor HNF4? regulates metabolism of endogenous methylarginines and ?-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2. Sci Rep. 2016;6:35503 pubmed publisher
  • immunocytochemistry; African green monkey; 1:25; fig 1
  • western blot; African green monkey; 1:250; fig 1
Li C, Shu Z, Lee S, Gupta M, Jansson T, Nathanielsz P, et al. Effects of maternal nutrient restriction, intrauterine growth restriction, and glucocorticoid exposure on phosphoenolpyruvate carboxykinase-1 expression in fetal baboon hepatocytes in vitro. J Med Primatol. 2013;42:211-9 pubmed publisher
Zhu S, Rezvani M, Harbell J, Mattis A, Wolfe A, Benet L, et al. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 2014;508:93-7 pubmed publisher
product information
Product Type :
Antibody
Product Name :
HNF4A Monoclonal Antibody (H1415)
Catalog # :
417700
Quantity :
100 µg
Price :
US 449.00
Clonality :
Monoclonal
Purity :
Ammonium sulfate precipitation
Host :
Mouse
Reactivity :
Human, Rat
Applications :
ChIP assay: Assay-dependent, ELISA: 0.3 µg/mL, Gel Shift: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry: 10-20 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
Species :
Human, Rat
Clone :
H1415
Isotype :
IgG2a
Storage :
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Description :
Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.
Immunogen :
Baculovirus-expressed recombinant human HNF4-alpha (393-461 aa)
Format :
Liquid
Applications w/Dilutions :
ChIP assay: Assay-dependent, ELISA: 0.3 µg/mL, Gel Shift: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry: 10-20 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 1 µg/mL
Aliases :
alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA