Cathepsin L Monoclonal Antibody (3G10) | Invitrogen 415500 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cathepsin L Monoclonal Antibody (3G10)

catalog :

415500

quantity :

200 uL

price :

US 502.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G10

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry

citations: 1

Reference
Niessen S, Dix M, Barbas S, Potter Z, Lu S, Brodsky O, et al. Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. Cell Chem Biol. 2017;24:1388-1400.e7 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cathepsin L Monoclonal Antibody (3G10)

Catalog # :

415500

Quantity :

200 uL

Price :

US 502.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: 1 ug/mL

Species :

Human, Mouse

Clone :

3G10

Isotype :

IgG1

Storage :

-20 C

Description :

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Immunogen :

Purified human procathepsin L from conditioned culture medium of human non-small cell lung cancer EPLC (32M1) cell line.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: 1 ug/mL

Aliases :

1190035F06Rik; Cat L; cathepsin L; Cathepsin L1; Cathepsin L1 heavy chain; Cathepsin L1 light chain; CATHL; CatL; CP-2; Ctsl; CTSL1; cyclic protein 2; fs; furless; major excreted protein; MEP; nackt; nkt; p39 cysteine proteinase; Procathepsin L