SOX2 Monoclonal Antibody (Btjce), eFluor 570, eBioscience | Invitrogen 41-9811-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX2 Monoclonal Antibody (Btjce), eFluor 570, eBioscience

catalog :

41-9811-82

quantity :

100 ug

price :

US 451.00

clonality :

monoclonal

host :

rat

conjugate :

eFluor 570

clone name :

Btjce

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry

citations: 27

Reference
Wang C, Zhang L, Cao M, Fu Z, Wang H, Zhang S, et al. Thioredoxin facilitates hepatocellular carcinoma stemness and metastasis by increasing BACH1 stability to activate the AKT/mTOR pathway. FASEB J. 2023;37:e22943 pubmed publisher
Frederico B, Martins I, Chapela D, Gasparrini F, Chakravarty P, Ackels T, et al. DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential. Dev Cell. 2022;57:1957-1975.e9 pubmed publisher
B xe9 renger Currias N, Mircea M, Adegeest E, van den Berg P, Feliksik M, Hochane M, et al. A gastruloid model of the interaction between embryonic and extra-embryonic cell types. J Tissue Eng. 2022;13:20417314221103042 pubmed publisher
Belgacemi R, Danopoulos S, Deutsch G, Glass I, Dormoy V, Bellusci S, et al. Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis. Int J Mol Sci. 2022;23: pubmed publisher
Lambert E, Saha O, Soares Landeira B, Melo de Farias A, Hermant X, Carrier A, et al. The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects. Acta Neuropathol Commun. 2022;10:4 pubmed publisher
Valcourt J, Huang R, Kundu S, Venkatasubramanian D, Kingston R, Ramanathan S. Modulating mesendoderm competence during human germ layer differentiation. Cell Rep. 2021;37:109990 pubmed publisher
Mirzaei R, Gordon A, Zemp F, Kumar M, Sarkar S, Luchman H, et al. PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NFκB pathway. Sci Adv. 2021;7:eabh2148 pubmed publisher
Suong D, Imamura K, Inoue I, Kabai R, Sakamoto S, Okumura T, et al. Induction of inverted morphology in brain organoids by vertical-mixing bioreactors. Commun Biol. 2021;4:1213 pubmed publisher
Austin S, Gabarr xf3 Solanas R, Rigo P, Paun O, Harris L, Guillemot F, et al. Wnt/β-catenin signalling is dispensable for adult neural stem cell homeostasis and activation. Development. 2021;148: pubmed publisher
Morgani S, Hadjantonakis A. Quantitative analysis of signaling responses during mouse primordial germ cell specification. Biol Open. 2021;10: pubmed publisher
Kojic M, Gawda T, Gaik M, Begg A, Salerno Kochan A, Kurniawan N, et al. Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype. Nat Commun. 2021;12:2678 pubmed publisher
Morgani S, Su J, Nichols J, Massague J, Hadjantonakis A. The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. elife. 2021;10: pubmed publisher
Sugiura A, Shimizu T, Kameyama T, Maruo T, Kedashiro S, Miyata M, et al. Identification of Sox2 and NeuN Double-Positive Cells in the Mouse Hypothalamic Arcuate Nucleus and Their Reduction in Number With Aging. Front Aging Neurosci. 2020;12:609911 pubmed publisher
Dzikowski L, Mirzaei R, Sarkar S, Kumar M, Bose P, Bellail A, et al. Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor-initiating cells. Brain Pathol. 2021;31:e12947 pubmed publisher
Siljee S, Buchanan O, Brasch H, Bockett N, Patel J, Paterson E, et al. Cancer Stem Cells in Metastatic Head and Neck Cutaneous Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Cells. 2021;10: pubmed publisher
Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo G, et al. Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Cell Stem Cell. 2021;28:453-471.e8 pubmed publisher
Siljee S, Pilkington T, Brasch H, Bockett N, Patel J, Paterson E, et al. Cancer Stem Cells in Head and Neck Metastatic Malignant Melanoma Express Components of the Renin-Angiotensin System. Life (Basel). 2020;10: pubmed publisher
Ramos Ibeas P, Lamas Toranzo I, Martínez Moro Á, de Frutos C, Quiroga A, Zurita E, et al. Embryonic disc formation following post-hatching bovine embryo development in vitro. Reproduction. 2020;160:579-589 pubmed publisher
Trus I, Bérubé N, Jiang P, Rak J, Gerdts V, Karniychuk U. Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells. Viruses. 2020;12: pubmed publisher
Lazarus K, Hadi F, Zambon E, Bach K, Santolla M, Watson J, et al. BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma. Nat Commun. 2018;9:3327 pubmed publisher
Yang Y, Riccio P, Schotsaert M, Mori M, LU J, Lee D, et al. Spatial-Temporal Lineage Restrictions of Embryonic p63+ Progenitors Establish Distinct Stem Cell Pools in Adult Airways. Dev Cell. 2018;44:752-761.e4 pubmed publisher
Morgani S, Metzger J, Nichols J, Siggia E, Hadjantonakis A. Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. elife. 2018;7: pubmed publisher
Alexandrova S, Kalkan T, Humphreys P, Riddell A, Scognamiglio R, Trumpp A, et al. Selection and dynamics of embryonic stem cell integration into early mouse embryos. Development. 2016;143:24-34 pubmed publisher
Yamamizu K, Schlessinger D, Ko M. SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1). Development. 2014;141:4254-66 pubmed publisher
Park I, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, et al. Disease-specific induced pluripotent stem cells. Cell. 2008;134:877-86 pubmed publisher
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-72 pubmed
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663-76 pubmed

product information

Product Type :

Antibody

Product Name :

SOX2 Monoclonal Antibody (Btjce), eFluor 570, eBioscience

Catalog # :

41-9811-82

Quantity :

100 ug

Price :

US 451.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry: Assay-Dependent

Species :

Human, Mouse

Clone :

Btjce

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry: Assay-Dependent

Aliases :

ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389