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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cathepsin B Monoclonal Antibody (4B11)
catalog :
41-4800
quantity :
100 µg
price :
US 668
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B11
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 7l
Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed publisher
Alhajala H, Nguyen H, Shabani S, Best B, Kaushal M, Al Gizawiy M, et al. Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes. Oncotarget. 2018;9:34122-34131 pubmed publisher
Klose A, Wilbrand Hennes A, Zigrino P, Weber E, Krieg T, Mauch C, et al. Contact of high-invasive, but not low-invasive, melanoma cells to native collagen I induces the release of mature cathepsin B. Int J Cancer. 2006;118:2735-43 pubmed
product information
Product Type :
Antibody
Product Name :
Cathepsin B Monoclonal Antibody (4B11)
Catalog # :
41-4800
Quantity :
100 µg
Price :
US 668
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Clone :
4B11
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Cathepsin B is a lysosomal cysteine protease that has been implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy and tumor metastasis.
Immunogen :
Recombinant human pro-cathepsin B protein
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: Assay-dependent
Aliases :
amyloid precursor protein secretase; APP secretase; APPS; cathepsin B; Cathepsin B heavy chain; Cathepsin B light chain; Cathepsin B1; CB; CPSB; Ctsb; cysteine protease; RSG-2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA