product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SSEA4 Monoclonal Antibody (MC-813-70)
catalog :
41-4000
quantity :
100 µg
price :
US 450
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MC-813-70
reactivity :
human, domestic rabbit
application :
immunocytochemistry, flow cytometry, other
more info or order :
citations: 51
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:300; loading ...; fig 4a
Battaglia R, Beltran A, Delic S, Dumitru R, Robinson J, Kabiraj P, et al. Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity. elife. 2019;8: pubmed publisher
  • immunocytochemistry; human; fig s2i
Ercan E, Han J, Di Nardo A, Winden K, Han M, Hoyo L, et al. Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex. J Exp Med. 2017;214:681-697 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:500; fig 3e
Sang C, Cao X, Chen F, Yang X, Zhang Y. Differential Characterization of Two Kinds of Stem Cells Isolated from Rabbit Nucleus Pulposus and Annulus Fibrosus. Stem Cells Int. 2016;2016:8283257 pubmed
  • immunocytochemistry; human; 1:200; loading ...; tbl 1
Quintanilla R, Asprer J, Sylakowski K, Lakshmipathy U. Kinetic Measurement and Real Time Visualization of Somatic Reprogramming. J Vis Exp. 2016;: pubmed publisher
  • immunocytochemistry; human; fig 1
Reboun M, Rybová J, Dobrovolny R, Vcelak J, Veselková T, Storkanova G, et al. X-Chromosome Inactivation Analysis in Different Cell Types and Induced Pluripotent Stem Cells Elucidates the Disease Mechanism in a Rare Case of Mucopolysaccharidosis Type II in a Female. Folia Biol (Praha). 2016;62:82-9 pubmed
  • immunocytochemistry; domestic rabbit; 1:250; fig 1
Zhang L, Chen S, Chang P, Bao N, Yang C, Ti Y, et al. Harmful Effects of Leukocyte-Rich Platelet-Rich Plasma on Rabbit Tendon Stem Cells In Vitro. Am J Sports Med. 2016;44:1941-51 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:500; fig 4
Huang H, Wang S, Gui J, Shen H. A study to identify and characterize the stem/progenitor cell in rabbit meniscus. Cytotechnology. 2016;68:2083-103 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 1
Alves C, Dariolli R, Jorge F, Monteiro M, Maximino J, Martins R, et al. Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration. Front Cell Neurosci. 2015;9:289 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:500
Ding Z, Huang H. Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair. BMC Musculoskelet Disord. 2015;16:65 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:200
Liu C, Guo Q, Li J, Wang S, Wang Y, Li B, et al. Identification of rabbit annulus fibrosus-derived stem cells. PLoS ONE. 2014;9:e108239 pubmed publisher
  • immunocytochemistry; human; 1:350
Zhang J, Wang J. Prostaglandin E2 (PGE2) exerts biphasic effects on human tendon stem cells. PLoS ONE. 2014;9:e87706 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 6
Alvarez Gonzalez C, Duggleby R, Vagaska B, Querol S, Gomez S, Ferretti P, et al. Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity. PLoS ONE. 2013;8:e67968 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 3
Zhang J, Pan T, Im H, Fu F, Wang J. Differential properties of human ACL and MCL stem cells may be responsible for their differential healing capacity. BMC Med. 2011;9:68 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 8
Ruff D, Macarthur C, Tran H, Bergseid J, Tian J, Shannon M, et al. Applications of quantitative polymerase chain reaction protein assays during reprogramming. Stem Cells Dev. 2012;21:530-8 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:500
Zhang J, Wang J. Characterization of differential properties of rabbit tendon stem cells and tenocytes. BMC Musculoskelet Disord. 2010;11:10 pubmed publisher
Hekman K, Koss K, Ivancic D, He C, Wertheim J. Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase. Stem Cells Transl Med. 2022;11:1151-1164 pubmed publisher
Bchetnia M, Martineau L, Racine V, Powell J, McCuaig C, Morin C, et al. Generation of three induced pluripotent stem cell lines (UQACi003-A, UQACi004-A, and UQACi006-A) from three patients with KRT5 epidermolysis bullosa simplex mutations. Stem Cell Res. 2022;60:102726 pubmed publisher
Raad S, David A, Chung W, Faure C. Generation of three induced pluripotent stem cells lines from patients with esophageal atresia/tracheoesophageal fistula type C. Stem Cell Res. 2022;60:102711 pubmed publisher
Schuster J, de Guidi C, Fatima A, Sobol M, Dahl N. Syndromic RNA polymerase II insufficiency: Generation of a human induced pluripotent stem cell line (UUIGPi002A-5) with a heterozygous disruption of POLR2A. Stem Cell Res. 2021;57:102577 pubmed publisher
Ye T, Duan Y, Tsang H, Xu H, Chen Y, Cao H, et al. Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases. Commun Biol. 2021;4:195 pubmed publisher
Alowaysi M, Astro V, Fiacco E, Alzahrani F, Alkuraya F, Adamo A. Generation of iPSC lines (KAUSTi011-A, KAUSTi011-B) from a Saudi patient with epileptic encephalopathy carrying homozygous mutation in the GLP1R gene. Stem Cell Res. 2020;50:102148 pubmed publisher
Vasylovska S, Schuster J, Brboric A, Carlsson P, Dahl N, Lau J. Generation of human induced pluripotent stem cell (iPSC) lines (UUMCBi001-A, UUMCBi002-A) from two healthy donors. Stem Cell Res. 2020;50:102114 pubmed publisher
Alowaysi M, Fiacco E, Astro V, Adamo A. Generation of two iPSC lines (KAUSTi001-A, KAUSTi002-A) from a rare high-grade Klinefelter Syndrome patient (49-XXXXY) carrying a balanced translocation t(4,11) (q35,q23). Stem Cell Res. 2020;49:102098 pubmed publisher
Alowaysi M, Fiacco E, Astro V, Adamo A. Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B). Stem Cell Res. 2020;49:102042 pubmed publisher
de Matos A, Bl xe1 zquez S xe1 nchez M, Bento Oliveira A, de Almeida R, Nunes R, Lopes P, et al. Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease. J Med Chem. 2020;63:11663-11690 pubmed publisher
Cowan C, Renner M, De Gennaro M, Gross Scherf B, Goldblum D, Hou Y, et al. Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell. 2020;182:1623-1640.e34 pubmed publisher
Chen S, Lai W, Zhang W, Chen Q, Zhou L, So K, et al. Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons. Neural Regen Res. 2020;15:2335-2343 pubmed publisher
Fatima A, Schuster J, Akram T, Sobol M, Hoeber J, Dahl N. Generation of a human Neurochondrin deficient iPSC line KICRi002-A-3 using CRISPR/Cas9. Stem Cell Res. 2020;44:101758 pubmed publisher
Fatima A, Schuster J, Akram T, González C, Sobol M, Hoeber J, et al. Incontinentia pigmenti: Generation of an IKBKG deficient human iPSC line (KICRi002-A-1) on a 46,XY background using CRISPR/Cas9. Stem Cell Res. 2020;44:101739 pubmed publisher
Schuster J, Fatima A, Sobol M, Norradin F, Laan L, Dahl N. Generation of three human induced pluripotent stem cell (iPSC) lines from three patients with Dravet syndrome carrying distinct SCN1A gene mutations. Stem Cell Res. 2019;39:101523 pubmed publisher
Xing Q, Lin A, Su Z, Liu C, Huang W, Guo W, et al. Retrograde monosynaptic tracing through an engineered human embryonic stem cell line reveals synaptic inputs from host neurons to grafted cells. Cell Regen (Lond). 2019;8:1-8 pubmed publisher
Schuster J, Fatima A, Schwarz F, Klar J, Laan L, Dahl N. Generation of human induced pluripotent stem cell (iPSC) lines from three patients with von Hippel-Lindau syndrome carrying distinct VHL gene mutations. Stem Cell Res. 2019;38:101474 pubmed publisher
Huang G, Chen S, Chen X, Zheng J, Xu Z, Doostparast Torshizi A, et al. Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons. Front Neuroanat. 2019;13:23 pubmed publisher
Almansoori A, Khentii N, Kim B, Kim S, Lee J. Mesenchymal Stem Cell Therapy in Submandibular Salivary Gland Allotransplantation: Experimental Study. Transplantation. 2019;103:1111-1120 pubmed publisher
Zhang J, Nie D, Rocha J, Hogan M, Wang J. Characterization of the structure, cells, and cellular mechanobiological response of human plantar fascia. J Tissue Eng. 2018;9:2041731418801103 pubmed publisher
Moraveji S, Esfandiari F, Sharbatoghli M, Taleahmad S, Nikeghbalian S, Shahverdi A, et al. Optimizing methods for human testicular tissue cryopreservation and spermatogonial stem cell isolation. J Cell Biochem. 2019;120:613-621 pubmed publisher
Zhang J, Wang J. Maintenance of Tendon Stem/Progenitor Cells in Culture. Methods Mol Biol. 2018;1842:217-228 pubmed publisher
Guo Q, Zhou P, Li B. Identification and Characterizations of Annulus Fibrosus-Derived Stem Cells. Methods Mol Biol. 2018;1842:207-216 pubmed publisher
Petkov S, Glage S, Niemann H. Mouse iPSC generated with porcine reprogramming factors as a model for studying the effects of non-silenced heterologous transgenes on pluripotency. J Stem Cells Regen Med. 2017;13:20-28 pubmed
Ho J, Cattoglio C, McSwiggen D, Tjian R, Fong Y. Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells. Genes Dev. 2017;31:830-844 pubmed publisher
Wang C, Cao X, Zhang Y. A novel bioactive osteogenesis scaffold delivers ascorbic acid, β-glycerophosphate, and dexamethasone in vivo to promote bone regeneration. Oncotarget. 2017;8:31612-31625 pubmed publisher
Wei Y, Zhou X, Huang W, Long P, Xiao L, Zhang T, et al. Generation of trophoblast-like cells from the amnion in vitro: A novel cellular model for trophoblast development. Placenta. 2017;51:28-37 pubmed publisher
Josowitz R, Mulero Navarro S, Rodriguez N, Falce C, Cohen N, Ullian E, et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016;7:355-369 pubmed publisher
Favaedi R, Shahhoseini M, Pakzad M, Mollamohammadi S, Baharvand H. Comparative epigenetic evaluation of human embryonic stem and induced pluripotent cells. Int J Dev Biol. 2016;60:103-10 pubmed publisher
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
Huang K, Du J, Ma N, Liu J, Wu P, Dong X, et al. GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment. Cell Regen (Lond). 2015;4:4 pubmed publisher
Eller C, Yang G, Ouerfelli O, Raines R. Affinity of monoclonal antibodies for Globo-series glycans. Carbohydr Res. 2014;397:1-6 pubmed publisher
Quintanilla R. Cellular characterization of human pluripotent stem cells. Methods Mol Biol. 2013;997:179-90 pubmed publisher
Zhang J, Wang J. BMP-2 mediates PGE(2) -induced reduction of proliferation and osteogenic differentiation of human tendon stem cells. J Orthop Res. 2012;30:47-52 pubmed publisher
Schwartz C, Cheng A, Mughal M, Mattson M, Yao P. Clathrin assembly proteins AP180 and CALM in the embryonic rat brain. J Comp Neurol. 2010;518:3803-18 pubmed publisher
Kannagi R, Cochran N, Ishigami F, Hakomori S, Andrews P, Knowles B, et al. Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. EMBO J. 1983;2:2355-61 pubmed
product information
Product Type :
Antibody
Product Name :
SSEA4 Monoclonal Antibody (MC-813-70)
Catalog # :
41-4000
Quantity :
100 µg
Price :
US 450
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent
Species :
Human, Mouse
Clone :
MC-813-70
Isotype :
IgG3
Storage :
-20°C
Description :
SSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
Immunogen :
Human SSEA4 antigen
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent
Aliases :
SSEA-4; stage-specific embryonic antigen 4
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA