CD323 (JAM3) Monoclonal Antibody (SHM33), eFluor™ 570, eBioscience | Invitrogen 41-3239-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD323 (JAM3) Monoclonal Antibody (SHM33), eFluor™ 570, eBioscience

catalog :

41-3239-80

quantity :

25 µg

price :

US 166

clonality :

monoclonal

host :

mouse

conjugate :

eFluor 570

clone name :

SHM33

reactivity :

human

application :

immunohistochemistry, immunocytochemistry

citations: 4

Reference
Immenschuh S, Naidu S, Chavakis T, Beschmann H, Ludwig R, Santoso S. Transcriptional induction of junctional adhesion molecule-C gene expression in activated T cells. J Leukoc Biol. 2009;85:796-803 pubmed publisher
Praetor A, McBride J, Chiu H, Rangell L, Cabote L, Lee W, et al. Genetic deletion of JAM-C reveals a role in myeloid progenitor generation. Blood. 2009;113:1919-28 pubmed publisher
Mandicourt G, Iden S, Ebnet K, Aurrand Lions M, Imhof B. JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration. J Biol Chem. 2007;282:1830-7 pubmed
Aurrand Lions M, Lamagna C, Dangerfield J, Wang S, Herrera P, Nourshargh S, et al. Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J Immunol. 2005;174:6406-15 pubmed

product information

Product Type :

Antibody

Product Name :

CD323 (JAM3) Monoclonal Antibody (SHM33), eFluor™ 570, eBioscience

Catalog # :

41-3239-80

Quantity :

25 µg

Price :

US 166

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1 µg/mL, Immunohistochemistry: Assay-Dependent

Species :

Human

Clone :

SHM33

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

JAM3 is involved in tight junctions and represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1 µg/mL, Immunohistochemistry: Assay-Dependent

Aliases :

1110002N23Rik; JAM-2; JAM3; JAM-3; JAMC; JAM-C; Jcam3; junction adhesion molecule 3; junction cell adhesion molecule 3; junction cell adhesion molecule C; junctional adhesion molecule 3; Junctional adhesion molecule C; sJAM-C; Soluble form of JAM-C; UNQ859/PRO1868