This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
EB1 Monoclonal Antibody (1A11/4)
catalog :
41-2100
quantity :
100 ug
price :
US 520.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A11/4

The same clone is also sold as:
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunocytochemistry
citations: 4
Reference
Dema A, Charafeddine R, Rahgozar S, van Haren J, Wittmann T. Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant. elife. 2023;12: pubmed publisher
Furey C, Astar H, Walsh D. Human Cytomegalovirus Exploits TACC3 To Control Microtubule Dynamics and Late Stages of Infection. J Virol. 2021;95:e0082121 pubmed publisher
Furey C, Jovasevic V, Walsh D. TACC3 Regulates Microtubule Plus-End Dynamics and Cargo Transport in Interphase Cells. Cell Rep. 2020;30:269-283.e6 pubmed publisher
van Haren J, Charafeddine R, Ettinger A, Wang H, Hahn K, Wittmann T. Local control of intracellular microtubule dynamics by EB1 photodissociation. Nat Cell Biol. 2018;20:252-261 pubmed publisher
product information
Product Type :
Antibody
Product Name :
EB1 Monoclonal Antibody (1A11/4)
Catalog # :
41-2100
Quantity :
100 ug
Price :
US 520.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Canine, Human, Mouse, Rat
Applications :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: 1-3 ug/mL
Species :
Canine, Human, Mouse, Rat
Clone :
1A11/4
Isotype :
IgG2b, kappa
Storage :
-20 C
Description :
EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. The MAPRE genes encode the EB1 family proteins. The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively. EB1 family members appear to be expressed ubiquitously. The EB1 (MAPRE1) gene, at 20q11. 2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia. EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
Immunogen :
Recombinant protein encompassing the N-terminal domain of the human EB1 protein
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: 1-3 ug/mL
Aliases :
5530600P05Rik; adenomatosis polyposis coli binding protein Eb1; adenomatous polyposis coli-binding protein EB1; AI462499; AI504412; APC-binding protein EB1; AW260097; BIM1p; D2Ertd459e; Eb1; end-binding protein 1; Mapre1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein RP/EB family member 1-like protein; microtubule-associated protein, RP/EB family, member 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA