Connexin 45 Monoclonal Antibody (ZC014) | Invitrogen 41-1700 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Connexin 45 Monoclonal Antibody (ZC014)

catalog :

41-1700

quantity :

100 ug

price :

US 414.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZC014

reactivity :

mouse

application :

immunohistochemistry, immunohistochemistry - frozen section

citations: 1

Reference
Li X, Kamasawa N, Ciolofan C, Olson C, Lu S, Davidson K, et al. Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1. J Neurosci. 2008;28:9769-89 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Connexin 45 Monoclonal Antibody (ZC014)

Catalog # :

41-1700

Quantity :

100 ug

Price :

US 414.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Mouse

Applications :

ELISA: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent

Species :

Mouse

Clone :

ZC014

Isotype :

IgG1, kappa

Storage :

-20 C

Description :

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.

Immunogen :

Synthetic peptide derived from the C-terminal region of the mouse connexin 45 protein

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent

Aliases :

C130009G16Rik; Cnx45; connexin 45; connexin-45; CTC-296K1.4; CX45; Cxn-45; Gap junction alpha-7 protein; gap junction channel protein connexin 45; gap junction gamma-1 protein; gap junction membrane channel protein alpha 7; gap junction protein gamma 1; gap junction protein, gamma 1; gap junction protein, gamma 1, 45kDa; Gja7; Gja-7; GJC1