Caveolin 2 Monoclonal Antibody (ZC013) | Invitrogen 41-0700 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caveolin 2 Monoclonal Antibody (ZC013)

catalog :

41-0700

quantity :

100 µg

price :

US 500

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZC013

reactivity :

human

application :

western blot, ELISA

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; fig 4	Yamasaki T, Seki N, Yoshino H, Itesako T, Hidaka H, Yamada Y, et al. MicroRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway. J Urol. 2013;190:1059-68 pubmed publisher
	Wang L, Yang C, Wang Q, Liu Q, Wang Y, Zhou J, et al. Homotrimer cavin1 interacts with caveolin1 to facilitate tumor growth and activate microglia through extracellular vesicles in glioma. Theranostics. 2020;10:6674-6694 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Caveolin 2 Monoclonal Antibody (ZC013)

Catalog # :

41-0700

Quantity :

100 µg

Price :

US 500

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Western Blot: 1:1,000

Species :

Human

Clone :

ZC013

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human caveolin-2 protein

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Western Blot: 1:1,000

Aliases :

AI447843; CAV; CAV2; caveolae; caveolae protein, 20-kD; caveolin 2; caveolin 2 isoform a and b; caveolin-2; MGC12294; Phospho-CAV2

more info or order :

Invitrogen product webpage