CD73 Monoclonal Antibody (7G2) | Invitrogen 41-0200 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD73 Monoclonal Antibody (7G2)

catalog :

41-0200

quantity :

100 µg

price :

US 446

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7G2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; fig s1g	Sanchez V, Villalba N, Fiore L, Luzzani C, Miriuka S, Boveris A, et al. Characterization of Tunneling Nanotubes in Wharton's jelly Mesenchymal Stem Cells. An Intercellular Exchange of Components between Neighboring Cells. Stem Cell Rev. 2017;13:491-498 pubmed publisher
immunocytochemistry; human; 1:100; loading ...; tbl 1	Quintanilla R, Asprer J, Sylakowski K, Lakshmipathy U. Kinetic Measurement and Real Time Visualization of Somatic Reprogramming. J Vis Exp. 2016;: pubmed publisher
ELISA; human; 1 ug/ml; fig 5a	Hatch A, Sibley A, Starr M, Brady J, Jiang C, Jia J, et al. Blood-based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance). Cancer Med. 2016;5:2249-60 pubmed publisher
immunohistochemistry - frozen section; human; 1:100	Zimmerlin L, Donnenberg V, Rubin J, Donnenberg A. Mesenchymal markers on human adipose stem/progenitor cells. Cytometry A. 2013;83:134-40 pubmed publisher
	Naseer N, Mustafa M, Latief N, Fazal N, Tariq M, Afreen A, et al. Sarcococca saligna fabricated gold nanoparticles alleviated in vitro oxidative stress and inflammation in human adipose-derived stem cells. J Biomed Mater Res B Appl Biomater. 2023;111:2032-2043 pubmed publisher
	Wright A, Snyder L, Knights K, He H, Springer N, Lillich J, et al. A Protocol for the Isolation, Culture, and Cryopreservation of Umbilical Cord-Derived Canine Mesenchymal Stromal Cells: Role of Cell Attachment in Long-Term Maintenance. Stem Cells Dev. 2020;29:695-713 pubmed publisher
	Lin T, Chen S, Chuang Y, Lan M, Chuang J, Wang P, et al. Mitochondrial Transfer of Wharton's Jelly Mesenchymal Stem Cells Eliminates Mutation Burden and Rescues Mitochondrial Bioenergetics in Rotenone-Stressed MELAS Fibroblasts. Oxid Med Cell Longev. 2019;2019:9537504 pubmed publisher
	Ferreira A, Cunha P, Carregal V, da Silva P, de Miranda M, Kunrath Lima M, et al. Extracellular Vesicles from Adipose-Derived Mesenchymal Stem/Stromal Cells Accelerate Migration and Activate AKT Pathway in Human Keratinocytes and Fibroblasts Independently of miR-205 Activity. Stem Cells Int. 2017;2017:9841035 pubmed publisher
	Madrigal A, Tan L, Zhao Y. Expression regulation and functional analysis of RGS2 and RGS4 in adipogenic and osteogenic differentiation of human mesenchymal stem cells. Biol Res. 2017;50:43 pubmed publisher
	Patkar C, Giaya K, Libraty D. Dengue virus type 2 modulates endothelial barrier function through CD73. Am J Trop Med Hyg. 2013;88:89-94 pubmed publisher
	Haasters F, Prall W, Anz D, Bourquin C, Pautke C, Endres S, et al. Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing. J Anat. 2009;214:759-67 pubmed publisher
	Thomson L, Ruedi J, Glass A, Moldenhauer G, Moller P, Low M, et al. Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5'-nucleotidase (CD73). Tissue Antigens. 1990;35:9-19 pubmed

product information

Product Type :

Antibody

Product Name :

CD73 Monoclonal Antibody (7G2)

Catalog # :

41-0200

Quantity :

100 µg

Price :

US 446

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-dependent, Functional Assay: Assay-dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-dependent, Immunoprecipitation: Assay-dependent, Inhibition Assays: Assay-dependent, Western Blot: 1 µg/mL

Species :

Human

Clone :

7G2

Isotype :

IgG2a, kappa

Storage :

-20°C

Description :

CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations. Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis. Two transcript variants encoding different isoforms of CD73 have been found.

Immunogen :

Highly purified human placental CD73 protein

Format :

Liquid

Applications w/Dilutions :

Aliases :

2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase

more info or order :

Invitrogen product webpage