CD8a Monoclonal Antibody (53-6.7), Brilliant Violet 421, eBioscience | Invitrogen 404-0081-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD8a Monoclonal Antibody (53-6.7), Brilliant Violet 421, eBioscience

catalog :

404-0081-80

quantity :

25 ug

price :

US 160.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

53-6.7

The same clone is also sold as:

Rockland Immunochemicals: 200-508-N77, 200-502-N77, 200-526-N77
BD Biosciences: 553030, 553027, 553032, 562283, 558733, 557959, 560247, 561967, 552877, 553031, 553036, 553033, 560182, 563332, 560776, 553028, 561093, 558106, 563068, 563898, 560778, 561109, 551162, 557668, 561966, 562315, 560469, 553029, 561092, 553035, 564459, 553026, 564422, 560471, 561097, 561094, 563046, 553034, 563234, 563786, 561095, 557654, 557682, 550281
Novus Biologicals: NBP2-80658, NBP1-49045
OriGene: AM08023LE-N, AM08023RC7-N, AM08023FC-S, AM08023PU-N, AM08023RP-S, AM08023BT-N, AM08023FC-N, AM08023RT-N, AM08023RP-N, AM08023AC7-N
Exbio: A4-579-C100, 1A-579-C025, A4-579-C025, 1P-579-C100, 1F-579-C100, PB-579-C100, 11-579-C025, 1A-579-C100, PB-579-C025, 11-579-C100, 12-579-C100
Tonbo Biosciences: 70-0081, 30-0081, 65-0081
BioLegend: 100798, 100777, 100707, 100765, 100732, 100704, 100721, 100768, 100748, 100759, 104011, 100708, 100779, 100783, 100731, 100787, 100741, 100766, 100790, 100722, 100769, 100763, 104009, 100751, 100758, 100788, 100793, 100723, 100776, 100770, 100702, 100713, 100705, 100782, 100709, 100746, 100727, 100738, 100701, 104007, 100733, 100749, 100752, 100791, 100780, 100796, 104008, 104013, 100797, 100789, 100730, 100747, 100742, 100764, 100753, 100728, 100785, 100706, 100755, 100743, 104006, 100762, 100767, 100714, 100775, 100739, 100750, 104014, 100734, 100761, 100773, 104012, 100794, 100725, 100772, 100795, 100711, 100744, 100737, 285050, 100740, 100726, 100729, 100710, 100792, 100781, 100703, 100712, 100724, 100771, 104005
Abcam: Ab25478
Santa Cruz Biotechnology: sc-18913 L, sc-18913
ichorbio: ICH1044UL, ICH1044
Bio-Rad: MCA2694, MCA2694T
R&D Systems: FAB116G-100, FAB116T-100UG, BAM116, FAB116F-100, MAB116-100, FAB116R-100UG, FAB116A-100, FAB116S-100UG, FAB116V-100UG, FAB116P-100
Bio X Cell: BE0004-1-5MG, BE0004-1-50MG, BE0004-1-100MG, BE0004-1-25MG, BE0004-1-1MG
Wuhan Fine Biotech Co.,Ltd.: PC55-30003, FITC-30003, APC-30003, PE-30003

reactivity :

mouse

application :

flow cytometry

citations: 1

Reference
Kim J, Qiao F, Singh A, Won J, Singh I. Efficacies of S-nitrosoglutathione (GSNO) and GSNO reductase inhibitor in SARS-CoV-2 spike protein induced acute lung disease in mice. Front Pharmacol. 2023;14:1304697 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD8a Monoclonal Antibody (53-6.7), Brilliant Violet 421, eBioscience

Catalog # :

404-0081-80

Quantity :

25 ug

Price :

US 160.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 ug/test

Species :

Mouse

Clone :

53-6.7

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha. Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells. Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test

Aliases :

BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein