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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ANGPTL4 Polyclonal Antibody
catalog :
40-9800
quantity :
100 µg
price :
US 430.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:100; fig 1h
  • immunohistochemistry; mouse; 1:100; fig 1e
Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
Avalle L, Raggi L, Monteleone E, Savino A, Viavattene D, Statello L, et al. STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts. Oncogene. 2022;41:1456-1467 pubmed publisher
Orozco Morales M, Rinaldi C, de Jong E, Lansley S, Gummer J, Olasz B, et al. PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective. iScience. 2022;25:103571 pubmed publisher
Jung K, Son M, Yan H, Fang Z, Kim J, Kim S, et al. ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a. EMBO Mol Med. 2020;12:e11222 pubmed publisher
Yang W, Huang Z, Wu J, Ding C, Murphy S, Chi J. A TAZ-ANGPTL4-NOX2 Axis Regulates Ferroptotic Cell Death and Chemoresistance in Epithelial Ovarian Cancer. Mol Cancer Res. 2020;18:79-90 pubmed publisher
Yellowley C, Toupadakis C, Vapniarsky N, Wong A. Circulating progenitor cells and the expression of Cxcl12, Cxcr4 and angiopoietin-like 4 during wound healing in the murine ear. PLoS ONE. 2019;14:e0222462 pubmed publisher
Liu N, Cui C, Sun Y, Zhang F, Wang S, Su G, et al. Hydrogen peroxide promotes the expression of angiopoietin like 4 in RAW264.7 macrophages via MAPK pathways. Mol Med Rep. 2017;16:6128-6133 pubmed publisher
product information
Product Type :
Antibody
Product Name :
ANGPTL4 Polyclonal Antibody
Catalog # :
40-9800
Quantity :
100 µg
Price :
US 430.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:20, Western Blot: Assay-dependent
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
Immunogen :
Synthetic peptide derived from an internal region of the human ANGTPL4 protein, which differs from rat and mouse by one and two conservative amino acid replacements, respectively
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:20, Western Blot: Assay-dependent
Aliases :
425O18-1; angiopoietin like 4; angiopoietin-like 4; angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; ANGPTL4; ANGPTL4 C-terminal chain; ANGPTL4 N-terminal chain; ARP4; Bk89; Farp; Fasting-i; Fasting-induced adipose factor; FIAF; fibrinogen/angiopoietin-related protein; HARP; hepatic angiopoietin-related protein; hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; Ng27; NL2; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PGAR; Pgarg; Pp1158; PPARG angiopoietin related protein; PSEC0166; Secreted protein Bk89; TGQTL; UNQ171; UNQ171/PRO197
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA