TEM7 Polyclonal Antibody | Invitrogen 40-9100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TEM7 Polyclonal Antibody

catalog :

40-9100

quantity :

100µg

price :

331 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

product information

Product Type :

Antibody

Product Name :

TEM7 Polyclonal Antibody

Catalog # :

40-9100

Quantity :

100µg

Price :

331 USD

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Western Blot: Assay Dependent

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20°C

Description :

Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human TEM7 protein, which differs from dog by one conservative amino acid replacement

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay Dependent

Aliases :

TEM3, TEM7, 2410003I07Rik, plexin domain-containing protein 1, tumor endothelial marker 3, tumor endothelial marker 7