Connexin 30.2 Polyclonal Antibody | Invitrogen 40-7400 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Connexin 30.2 Polyclonal Antibody

catalog :

40-7400

quantity :

100 ug

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 5

Reference
Bai X, Xu K, Xie L, Qiu Y, Chen S, Sun Y. The Dual Roles of Triiodothyronine in Regulating the Morphology of Hair Cells and Supporting Cells during Critical Periods of Mouse Cochlear Development. Int J Mol Sci. 2023;24: pubmed publisher
Pedrosa R, Wismans L, Sinke R, van der Weiden M, van Eijck C, Kros J, et al. Differential Expression of BOC, SPOCK2, and GJD3 Is Associated with Brain Metastasis of ER-Negative Breast Cancers. Cancers (Basel). 2021;13: pubmed publisher
Cooler S, Schwartz G. An offset ON-OFF receptive field is created by gap junctions between distinct types of retinal ganglion cells. Nat Neurosci. 2021;24:105-115 pubmed publisher
Zhang J, Vincent K, Peter A, Klos M, Cheng H, Huang S, et al. Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function. Circ Res. 2020;127:284-297 pubmed publisher
Bhattacharyya S, Duan J, Wang L, Li B, Bhakta M, Fernandez Perez A, et al. Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition. Sci Rep. 2019;9:2106 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Connexin 30.2 Polyclonal Antibody

Catalog # :

40-7400

Quantity :

100 ug

Price :

US 451.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 2-4 ug/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

Gap junctions are responsible for transport of ions and metabolites between adjacent cells. These structures are made of two hemichannels, each formed by six connexin molecules. Connexin 30, coded by Cjb6 gene, is a member of the connexin family and is highly expressed in brain and skin. Immunohistochemically connexin 30 was localized in astrocytes, at gap junctions between these cells and on the astrocyte side of gap junctions between astrocytes and oligodendrocytes. Co-localization with connexin 43 was also observed in this study. Cytoskeleton, especially actin filaments, are important components in the processes of assembly, trafficking and stabilization of connexin 30 gap junctions. Knock-out mice studies have also demonstrated that connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis highlighting the importance of this molecule in kidney. Further, in vitro studies have also demonstrated that connexin 30 overexpression enhances cell proliferation.

Immunogen :

Synthetic peptide derived from the c-term region of the mouse connexin 30.2 protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-4 ug/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1 ug/mL

Aliases :

connexin 30.2; connexin 31.9; Connexin-30.2; Connexin-31.9; Cx30.2; Cx31.9; gap junction alpha-11 protein; Gap junction chi-1 protein; gap junction delta-3 protein; gap junction membrane channel protein chi 1; gap junction protein delta 3; gap junction protein, delta 3; gap junction protein, delta 3, 31.9kDa; Gja11; GJC1; GJD3