JPH1 Polyclonal Antibody | Invitrogen 40-5100 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

JPH1 Polyclonal Antibody

catalog :

40-5100

quantity :

100 µg

price :

US 430

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 2b	Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, et al. RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure. Proc Natl Acad Sci U S A. 2019;116:6172-6180 pubmed publisher
western blot; rat; 1:500; loading ...; fig 5a	Kanzaki K, Watanabe D, Kuratani M, Yamada T, Matsunaga S, Wada M. Role of calpain in eccentric contraction-induced proteolysis of Ca2+-regulatory proteins and force depression in rat fast-twitch skeletal muscle. J Appl Physiol (1985). 2017;122:396-405 pubmed publisher
	Murzilli S, Serano M, Pietrangelo L, Protasi F, Paolini C. Structural Adaptation of the Excitation-Contraction Coupling Apparatus in Calsequestrin1-Null Mice during Postnatal Development. Biology (Basel). 2023;12: pubmed publisher
	Tammineni E, Figueroa L, Manno C, Varma D, Kraeva N, Ibarra C, et al. Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation. elife. 2023;12: pubmed publisher
	Chivet M, McCluskey M, Nicot A, Brocard J, Beaufils M, Giovannini D, et al. Huntingtin regulates calcium fluxes in skeletal muscle. J Gen Physiol. 2023;155: pubmed publisher
	Kanzaki K, Watanabe D, Aibara C, Kawakami Y, Yamada T, Takahashi Y, et al. l-arginine ingestion inhibits eccentric contraction-induced proteolysis and force deficit via S-nitrosylation of calpain. Physiol Rep. 2018;6: pubmed publisher
	Kesireddy V. Evaluation of adipose-derived stem cells for tissue-engineered muscle repair construct-mediated repair of a murine model of volumetric muscle loss injury. Int J Nanomedicine. 2016;11:1461-73 pubmed publisher
	Desmond P, Muriel J, Markwardt M, Rizzo M, Bloch R. Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle. J Biol Chem. 2015;290:27854-67 pubmed publisher
	Demonbreun A, Swanson K, Rossi A, Deveaux H, Earley J, Allen M, et al. Eps 15 Homology Domain (EHD)-1 Remodels Transverse Tubules in Skeletal Muscle. PLoS ONE. 2015;10:e0136679 pubmed publisher

product information

Product Type :

Antibody

Product Name :

JPH1 Polyclonal Antibody

Catalog # :

40-5100

Quantity :

100 µg

Price :

US 430

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Rat

Applications :

Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:50, Western Blot: 2-3 µg/mL

Species :

Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.

Immunogen :

Synthetic peptide derived from the C-terminal region of the mouse junctophilin-1 (JP-1, junctophilin type 1, JPH1) protein, which differs from rat by one non-conservative amino acid replacement

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:50, Western Blot: 2-3 µg/mL

Aliases :

CMT2K; ENSMUSG00000054314; JP1; JP-1; Jph1; junctophilin 1; junctophilin type 1; junctophilin type1; Junctophilin-1; mitsugumin72

more info or order :

Invitrogen product webpage