TXNIP Polyclonal Antibody | Invitrogen 40-4600 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TXNIP Polyclonal Antibody

catalog :

40-4600

quantity :

100µg

price :

US 331.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, cow

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 4	Chen D, Dang B, Huang J, Chen M, Wu D, Xu M, et al. MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1Î±-TWIST signaling axis in breast cancer. Oncotarget. 2015;6:32701-12 pubmed publisher
	Advani A, Gilbert R, Thai K, Gow R, Langham R, Cox A, et al. Expression, localization, and function of the thioredoxin system in diabetic nephropathy. J Am Soc Nephrol. 2009;20:730-41 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TXNIP Polyclonal Antibody

Catalog # :

40-4600

Quantity :

100µg

Price :

US 331.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Human

Applications :

Western Blot: Assay Dependent

Species :

Bovine, Human

Isotype :

IgG

Storage :

-20°C

Description :

Thioredoxin-interacting protein belongs to the arrestin family. It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1ß.

Immunogen :

Synthetic peptide derived from the N-terminal region of human VDUP-1

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay Dependent

Aliases :

EST01027, HHCPA78, THIF, VDUP1, thioredoxin binding protein 2, thioredoxin-binding protein 2, thioredoxin-interacting protein, upregulated by 1,25-dihydroxyvitamin D-3, vitamin D3 up-regulated protein 1