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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TXNIP Polyclonal Antibody
catalog :
40-3700
quantity :
100 µg
price :
US 450.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, bovine
application :
western blot, immunoprecipitation
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; mouse; fig 4
Du R, Wu F, Lu M, Shu X, Ding J, Wu G, et al. Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression. Redox Biol. 2016;9:178-187 pubmed publisher
Scrimieri R, Cazzaniga A, Castiglioni S, Maier J. Vitamin D Prevents High Glucose-Induced Lipid Droplets Accumulation in Cultured Endothelial Cells: The Role of Thioredoxin Interacting Protein. Biomedicines. 2021;9: pubmed publisher
Xue Y, Wang S, Rana P, West E, Hong C, Feng H, et al. AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa. elife. 2021;10: pubmed publisher
Qu S, Zhang C, Liu D, Wu J, Tian H, Lu L, et al. Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress. Oxid Med Cell Longev. 2020;2020:1740943 pubmed publisher
Noura M, Matsuo H, Koyama A, Adachi S, Masutani H. TXNIP induces growth arrest and enhances ABT263-induced apoptosis in mixed-lineage leukemia-rearranged acute myeloid leukemia cells. FEBS Open Bio. 2020;10:1532-1541 pubmed publisher
Mohamed I, Sheibani N, El Remessy A. Deletion of Thioredoxin-Interacting Protein (TXNIP) Abrogates High Fat Diet-induced Retinal Leukostasis, Barrier Dysfunction and Microvascular Degeneration in a Mouse Obesity Model. Int J Mol Sci. 2020;21: pubmed publisher
Streleckiene G, Inciuraite R, Juzenas S, Salteniene V, Steponaitiene R, Gyvyte U, et al. miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model. Int J Mol Sci. 2020;21: pubmed publisher
Kaplan N, Wang J, Wray B, Patel P, Yang W, Peng H, et al. Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population. Invest Ophthalmol Vis Sci. 2019;60:3570-3583 pubmed publisher
Kim H, Park H, Choi H, Chang Y, Park H, Shin J, et al. Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids. Stem Cell Reports. 2019;: pubmed publisher
Katsu Jiménez Y, Vázquez Calvo C, Maffezzini C, Halldin M, Peng X, Freyer C, et al. Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate. Diabetes. 2019;68:709-723 pubmed publisher
Li X, Kover K, Heruth D, Watkins D, Guo Y, Moore W, et al. Thioredoxin-interacting protein promotes high-glucose-induced macrovascular endothelial dysfunction. Biochem Biophys Res Commun. 2017;493:291-297 pubmed publisher
Coucha M, Mohamed I, Elshaer S, Mbata O, Bartasis M, El Remessy A. High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-reticulum-stress. World J Diabetes. 2017;8:56-65 pubmed publisher
product information
Product Type :
Antibody
Product Name :
TXNIP Polyclonal Antibody
Catalog # :
40-3700
Quantity :
100 µg
Price :
US 450.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Human
Applications :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Bovine, Human
Isotype :
IgG
Storage :
-20°C
Description :
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
Immunogen :
Synthetic peptide derived from the C-terminal region of human and rat VDUP-1 protein (Vitamin D3 Up-regulated Protein-1, TRX-interacting protein, TXNIP).
Format :
Liquid
Applications w/Dilutions :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
1200008J08Rik; AA682105; ARRDC6; EST01027; HHCPA78; hyperlipidemia 1; Hyplip1; Tbp-2; THIF; thioredoxin binding protein 2; thioredoxin binding protein-2; thioredoxin interacting protein; thioredoxin-binding protein 2; Thioredoxin-interacting protein; TXNIP; upregulated by 1,25-dihydroxyvitamin D-3; VDUP1; Vitamin D3 up-regulated protein 1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA