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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Arfaptin 2 Polyclonal Antibody
catalog :
40-2400
quantity :
100 µg
price :
US 430.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, western blot knockout validation
more info or order :
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 2a
  • immunocytochemistry; human; loading ...; fig 1f
Judith D, Jefferies H, Boeing S, Frith D, Snijders A, Tooze S. ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ. J Cell Biol. 2019;218:1634-1652 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Arfaptin 2 Polyclonal Antibody
Catalog # :
40-2400
Quantity :
100 µg
Price :
US 430.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 2 µg/mL, Western Blot: 2 µg/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). [UniProt]
Immunogen :
Synthetic peptide derived from the N-terminal region of the human Arfaptin 2 protein (ADP-ribosylation factor interacting protein 2, AFP2, Partner of Rac1, or POR1)
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 µg/mL, Western Blot: 2 µg/mL
Aliases :
2310002N04Rik; ADP ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; arfaptin-2; Arfip2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR; POR1; Protein POR1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA