Human CD258 (LIGHT) ELISA Standard Recombinant Protein, eBioscience™ | Invitrogen 39-8589-65 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human CD258 (LIGHT) ELISA Standard Recombinant Protein, eBioscience™

catalog :

39-8589-65

quantity :

4 pack

price :

115.00 USD

citations: 2

Reference
Miyagaki T, Sugaya M, Suga H, Ohmatsu H, Fujita H, Asano Y, et al. Serum-soluble herpes virus entry mediator levels reflect disease severity and Th2 environment in cutaneous T-cell lymphoma. Acta Derm Venereol. 2013;93:465-7 pubmed publisher
Del Rio M, Lucas C, Buhler L, Rayat G, Rodriguez Barbosa J. HVEM/LIGHT/BTLA/CD160 cosignaling pathways as targets for immune regulation. J Leukoc Biol. 2010;87:223-35 pubmed publisher

product information

Product Type :

Protein

Product Name :

Human CD258 (LIGHT) ELISA Standard Recombinant Protein, eBioscience™

Catalog # :

39-8589-65

Quantity :

4 pack

Price (USD) :

115.00 USD

Clonality :

Recombinant

Purity :

Affinity chromatography

Host :

NSO cells

Reactivity :

Human

Applications :

Control: Assay-Dependent, ELISA: Assay-Dependent

Species :

Human

Storage :

-80°C

Description :

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C. elegans death receptor-3) protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6). Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, ELISA: Assay-Dependent

Aliases :

CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726