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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
STRO-1 Monoclonal Antibody (STRO-1)
catalog :
39-8401
quantity :
100 µL
price :
US 430
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
STRO-1
reactivity :
human, domestic rabbit
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; domestic rabbit; 1:350; fig 3g
Sang C, Cao X, Chen F, Yang X, Zhang Y. Differential Characterization of Two Kinds of Stem Cells Isolated from Rabbit Nucleus Pulposus and Annulus Fibrosus. Stem Cells Int. 2016;2016:8283257 pubmed
  • immunocytochemistry; human; fig 5
Sadeghian Nodoushan F, Aflatoonian R, Borzouie Z, Akyash F, Fesahat F, Soleimani M, et al. Pluripotency and differentiation of cells from human testicular sperm extraction: An investigation of cell stemness. Mol Reprod Dev. 2016;83:312-23 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:400
Ding Z, Huang H. Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair. BMC Musculoskelet Disord. 2015;16:65 pubmed publisher
  • immunocytochemistry; human; 1:200
Zhang J, Wang J. Prostaglandin E2 (PGE2) exerts biphasic effects on human tendon stem cells. PLoS ONE. 2014;9:e87706 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 4
Zhang J, Pan T, Im H, Fu F, Wang J. Differential properties of human ACL and MCL stem cells may be responsible for their differential healing capacity. BMC Med. 2011;9:68 pubmed publisher
Li Y, Huang J, Wang J, Xia S, Ran H, Gao L, et al. Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis. J Neuroinflammation. 2023;20:49 pubmed publisher
Ivanov A, Danilova T, Kuznetsova A, Popova O, Yanushevich O. Decellularized Matrix Induced Spontaneous Odontogenic and Osteogenic Differentiation in Periodontal Cells. Biomolecules. 2023;13: pubmed publisher
Zhao Y, Cai B, Zhu W, Shi J, Wang Y, Si M. IL-1 Receptor Antagonist Protects the Osteogenesis Capability of Gingival-Derived Stem/Progenitor Cells under Inflammatory Microenvironment Induced by Porphyromonas gingivalis Lipopolysaccharides. Stem Cells Int. 2021;2021:6638575 pubmed publisher
Chang H, Chen I, Wang Y, Chang M, Tsai Y, Lan W, et al. Regulation of the regenerative activity of dental pulp stem cells from exfoliated deciduous teeth (SHED) of children by TGF-β1 is associated with ALK5/Smad2, TAK1, p38 and MEK/ERK signaling. Aging (Albany NY). 2020;12:21253-21272 pubmed publisher
Granger C, Hoyt A, Moran A, Becker B, Sedani A, Saigh S, et al. Cancer stem cells as a therapeutic target in 3D tumor models of human chondrosarcoma: An encouraging future for proline rich polypeptide‑1. Mol Med Rep. 2020;22:3747-3758 pubmed publisher
Moran A, Hoyt A, Sedani A, Granger C, Saigh S, Blonska M, et al. Proline‑rich polypeptide‑1 decreases cancer stem cell population by targeting BAFF chromatin‑remodeling complexes in human chondrosarcoma JJ012 cells. Oncol Rep. 2020;44:393-403 pubmed publisher
Liu X, Wang Z, Song W, Sun W, Hong R, Pothukuchi A, et al. Systematically transplanted human gingiva-derived mesenchymal stem cells regulate lipid metabolism and inflammation in hyperlipidemic mice with periodontitis. Exp Ther Med. 2020;19:672-682 pubmed publisher
Hira V, Breznik B, Vittori M, Loncq de Jong A, Mlakar J, Oostra R, et al. Similarities Between Stem Cell Niches in Glioblastoma and Bone Marrow: Rays of Hope for Novel Treatment Strategies. J Histochem Cytochem. 2020;68:33-57 pubmed publisher
Ahlfors J, Azimi A, El Ayoubi R, Velumian A, Vonderwalde I, Boscher C, et al. Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells. Stem Cell Res Ther. 2019;10:166 pubmed publisher
Winning L, El Karim I, Lundy F. A Comparative Analysis of the Osteogenic Potential of Dental Mesenchymal Stem Cells. Stem Cells Dev. 2019;: pubmed publisher
Fu X, Feng Y, Shao B, Zhang Y. Activation of the ERK/Creb/Bcl‑2 pathway protects periodontal ligament stem cells against hydrogen peroxide‑induced oxidative stress. Mol Med Rep. 2019;19:3649-3657 pubmed publisher
Zhao X, Zhu B, Duan Y, Wang X, Li D. The Effect of Smoking Behavior on Alveolar Bone Marrow Mesenchymal Stem Cells of Clinical Implant Patient. Biomed Res Int. 2018;2018:7672695 pubmed publisher
Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, et al. Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs. PLoS ONE. 2018;13:e0207760 pubmed publisher
Pei D, Sun J, Zhu C, Tian F, Jiao K, Anderson M, et al. Contribution of Mitophagy to Cell-Mediated Mineralization: Revisiting a 50-Year-Old Conundrum. Adv Sci (Weinh). 2018;5:1800873 pubmed publisher
Zhang J, Wang J. Maintenance of Tendon Stem/Progenitor Cells in Culture. Methods Mol Biol. 2018;1842:217-228 pubmed publisher
Kato M, Placencio Hickok V, Madhav A, Haldar S, Tripathi M, Billet S, et al. Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner. Oncogene. 2019;38:716-730 pubmed publisher
Baharaghdam S, Yousefi M, Movasaghpour A, Solali S, Talebi M, Ahani Nahayati M, et al. Effects of Hypoxia on Biology of Human Leukemia T-cell Line (MOLT-4 cells) Co-cultured with Bone Marrow Mesenchymal Stem Cells. Avicenna J Med Biotechnol. 2018;10:62-68 pubmed
Prusinski Fernung L, Yang Q, Sakamuro D, Kumari A, Mas A, Al Hendy A. Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells. Biol Reprod. 2018;99:735-748 pubmed publisher
Inubushi T, Nozawa S, Matsumoto K, Irie F, Yamaguchi Y. Aberrant perichondrial BMP signaling mediates multiple osteochondromagenesis in mice. JCI Insight. 2017;2: pubmed publisher
Tomasello L, Mauceri R, Coppola A, Pitrone M, Pizzo G, Campisi G, et al. Mesenchymal stem cells derived from inflamed dental pulpal and gingival tissue: a potential application for bone formation. Stem Cell Res Ther. 2017;8:179 pubmed publisher
Gonçalves A, Gershovich P, Rodrigues M, Reis R, Gomes M. Human adipose tissue-derived tenomodulin positive subpopulation of stem cells: A promising source of tendon progenitor cells. J Tissue Eng Regen Med. 2018;12:762-774 pubmed publisher
Mas A, Prusinski L, Yang Q, Díaz Gimeno P, Stone L, Diamond M, et al. Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy. Biol Reprod. 2017;96:70-80 pubmed publisher
Vega S, Liu E, Arvind V, Bushman J, Sung H, Becker M, et al. High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation. Exp Cell Res. 2017;351:11-23 pubmed publisher
Chen Y, Yao C, Huang C, Chang H, Young T. Hexosamine-Induced TGF-β Signaling and Osteogenic Differentiation of Dental Pulp Stem Cells Are Dependent on N-Acetylglucosaminyltransferase V. Biomed Res Int. 2015;2015:924397 pubmed publisher
Romagnoli C, Zonefrati R, Galli G, Puppi D, Pirosa A, Chiellini F, et al. In Vitro Behavior of Human Adipose Tissue-Derived Stem Cells on Poly(ε-caprolactone) Film for Bone Tissue Engineering Applications. Biomed Res Int. 2015;2015:323571 pubmed publisher
Dokić J, Tomic S, Markovic M, Milosavljević P, Colic M. Mesenchymal stem cells from periapical lesions modulate differentiation and functional properties of monocyte-derived dendritic cells. Eur J Immunol. 2013;43:1862-72 pubmed publisher
Pennington M, Grieve R, Sekhon J, Gregg P, Black N, van der Meulen J. Cemented, cementless, and hybrid prostheses for total hip replacement: cost effectiveness analysis. BMJ. 2013;346:f1026 pubmed publisher
Pereira L, Rubini M, Silva J, Oliveira D, Silva I, Poças Fonseca M, et al. Comparison of stem cell properties of cells isolated from normal and inflamed dental pulps. Int Endod J. 2012;45:1080-90 pubmed publisher
Liu Y, Goldberg A, Dennis J, Gronowicz G, Kuhn L. One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating. PLoS ONE. 2012;7:e33225 pubmed publisher
Lin G, Garcia M, Ning H, Banie L, Guo Y, Lue T, et al. Defining stem and progenitor cells within adipose tissue. Stem Cells Dev. 2008;17:1053-63 pubmed publisher
Simmons P, Torok Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 1991;78:55-62 pubmed
product information
Product Type :
Antibody
Product Name :
STRO-1 Monoclonal Antibody (STRO-1)
Catalog # :
39-8401
Quantity :
100 µL
Price :
US 430
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: 1:250
Species :
Human
Clone :
STRO-1
Isotype :
IgM
Storage :
-20°C
Description :
STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors, but does not react with committed progenitor cells (colony-forming unit granulocyte-macrophage (CFU-GM), erythroid bursts (BFU-E), and mixed colonies (CFU-Mix). From bone marrow cells, the frequency of fibroblast colony forming cells (CFU-F) is enriched approximately 100-fold in the STRO-1-positive/Glycophorin A-negative population than in the STRO-1-positive/Glycophorin A-positive population. When plated under long-term BM culture conditions, STRO-1-positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, and fibroblastic elements. A STRO-1-positive enriched subset of marrow cells is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts and chondrocytes. STRO-1 is a valuable antibody for the identification, isolation and functional characterization of human bone marrow stromal cell precursors.
Immunogen :
CD34+ human bone marrow cells
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: 1:250
Aliases :
STRO1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA