Human IL-29 (IFN lambda 1) ELISA Standard Recombinant Protein, eBioscience™ | Invitrogen 39-8299-65 product information

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product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human IL-29 (IFN lambda 1) ELISA Standard Recombinant Protein, eBioscience™

catalog :

39-8299-65

quantity :

4 pack

price :

115.00 USD

product information

Product Type :

Protein

Product Name :

Human IL-29 (IFN lambda 1) ELISA Standard Recombinant Protein, eBioscience™

Catalog # :

39-8299-65

Quantity :

4 pack

Price (USD) :

115.00 USD

Clonality :

Recombinant

Purity :

Affinity chromatography

Host :

E. coli

Reactivity :

Human

Applications :

Control: Assay-Dependent, ELISA: Assay-Dependent

Species :

Human

Storage :

-80°C

Description :

IFN-lambdas constitute a novel family of interferons that mediate the induction of anti-viral protection in a wide variety of cells. There are three members in this family, namely lambda1, lambda2, and lambda3, which are also known as IL-29, IL-28A, and IL-28B, respectively. Similar to type I IFNs, IFN-lambdas activate an intracellular signaling to promote gene expression. IFN-lambdas mediate their anti-viral protection through a class II cytokine receptor complex composed of two essential receptor proteins, CRF2-12/IFN-lambdaR1, which is unique to IFN-lambdas, and CFR2-4/IL-10R2, which is shared with IL-10, IL-22, and IL-26 receptors. The IFN-lambdas, IL-28 and IL-29, have recently been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells. DCs that differentiate in response to IFN-lambdas express high levels of class I and II MHC gene products, but low levels of costimulatory molecules. Moreover, these cells can specifically induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.

Format :

Liquid

Applications w/Dilutions :

Control: Assay-Dependent, ELISA: Assay-Dependent

Aliases :

Cytokine Zcyto21; FNL1; IFN lambda1; IFNL1; IFN-lambda-1; IL29; IL-29; ILN; interferon lambda 1; Interferon lambda1; interferon lambda-1; interferon, lambda 1; interferon-lambda-1; Interleukin; interleukin 29 (interferon, lambda 1); interleukin-29; ZCYTO21