Nucleolin Monoclonal Antibody (ZN004) | Invitrogen 39-6400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nucleolin Monoclonal Antibody (ZN004)

catalog :

39-6400

quantity :

100 ug

price :

US 520.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZN004

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 7	Mandic R, Marquardt A, Terhorst P, Ali U, Nowak Rossmann A, Cai C, et al. The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC. BMC Cancer. 2022;22:785 pubmed publisher
western blot; human; fig 4b	Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
immunocytochemistry; human; fig 1 western blot; human; fig 2	Hidalgo P, Anzures L, HernÃ¡ndez Mendoza A, Guerrero A, Wood C, ValdÃ©s M, et al. Morphological, Biochemical, and Functional Study of Viral Replication Compartments Isolated from Adenovirus-Infected Cells. J Virol. 2016;90:3411-27 pubmed publisher
immunocytochemistry; human; 1:100	Taketa D, Nydam M, Langenbacher A, Rodriguez D, Sanders E, De Tomaso A. Molecular evolution and in vitro characterization of Botryllus histocompatibility factor. Immunogenetics. 2015;67:605-23 pubmed publisher
immunocytochemistry; human; 1:100; fig 2	Pianta A, Puppin C, Passon N, Franzoni A, Romanello M, Tell G, et al. Nucleophosmin delocalization in thyroid tumour cells. Endocr Pathol. 2011;22:18-23 pubmed publisher
immunocytochemistry; human; 1:100	Pianta A, Fabbro D, Damiani D, Tiribelli M, Fanin R, Franzoni A, et al. Two novel NPM1 mutations in a therapy-responder AML patient. Hematol Oncol. 2010;28:151-5 pubmed publisher
immunocytochemistry; human western blot; human	Vascotto C, Fantini D, Romanello M, Cesaratto L, Deganuto M, Leonardi A, et al. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol. 2009;29:1834-54 pubmed publisher
	Buelvas N, Ugarte Vio I, Asencio Leal L, Mu xf1 oz Uribe M, Martin Martin A, Rojas Fern xe1 ndez A, et al. Indomethacin Induces Spermidine/Spermine-N1-Acetyltransferase-1 via the Nucleolin-CDK1 Axis and Synergizes with the Polyamine Oxidase Inhibitor Methoctramine in Lung Cancer Cells. Biomolecules. 2023;13: pubmed publisher
	Palmieri M, Catimel B, Mouradov D, Sakthianandeswaren A, Kapp E, Ang C, et al. PI3Kα Translocation Mediates Nuclear PtdIns(3,4,5)P3 Effector Signaling in Colorectal Cancer. Mol Cell Proteomics. 2023;22:100529 pubmed publisher
	Lazarchuk P, Nguyen V, Brunon S, Pavlova M, Sidorova J. Innate immunity mediator STING modulates nascent DNA metabolism at stalled forks in human cells. Front Mol Biosci. 2022;9:1048726 pubmed publisher
	Shukla S, Lazarchuk P, Pavlova M, Sidorova J. Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2. iScience. 2022;25:105464 pubmed publisher
	Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, et al. Nuclear speckle integrity and function require TAO2 kinase. Proc Natl Acad Sci U S A. 2022;119:e2206046119 pubmed publisher
	Shefer K, Boulos A, Gotea V, Arafat M, Ben Chaim Y, Muharram A, et al. A novel role for nucleolin in splice site selection. RNA Biol. 2022;19:333-352 pubmed publisher
	Fliedner A, Gregor A, Ferrazzi F, Ekici A, Sticht H, Zweier C. Loss of PHF6 leads to aberrant development of human neuron-like cells. Sci Rep. 2020;10:19030 pubmed publisher
	Ghosh S, Guimaraes J, Lanzafame M, Schmidt A, Syed A, Dimitriades B, et al. Prevention of dsRNA-induced interferon signaling by AGO1x is linked to breast cancer cell proliferation. EMBO J. 2020;39:e103922 pubmed publisher
	Ognibene M, Pezzolo A. Roniciclib down-regulates stemness and inhibits cell growth by inducing nucleolar stress in neuroblastoma. Sci Rep. 2020;10:12902 pubmed publisher
	Lazarchuk P, Hernandez Villanueva J, Pavlova M, Federation A, MacCoss M, Sidorova J. Mutual Balance of Histone Deacetylases 1 and 2 and the Acetyl Reader ATAD2 Regulates the Level of Acetylation of Histone H4 on Nascent Chromatin of Human Cells. Mol Cell Biol. 2020;40: pubmed publisher
	Gudkova D, Dergai O, Praz V, Herr W. HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs. Nucleic Acids Res. 2019;47:5792-5808 pubmed publisher
	Beyleveld G, Chin D, Moreno Del Olmo E, Carter J, Najera I, Cilloniz C, et al. Nucleolar Relocalization of RBM14 by Influenza A Virus NS1 Protein. mSphere. 2018;3: pubmed publisher
	Kehrli K, Sidorova J. Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells. Oncoscience. 2014;1:540-555 pubmed
	Park A, Won S, Pentecost M, Bartkowski W, Lee B. CRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein function. PLoS ONE. 2014;9:e95101 pubmed publisher
	Lirussi L, Antoniali G, Vascotto C, D Ambrosio C, Poletto M, Romanello M, et al. Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells. Mol Biol Cell. 2012;23:4079-96 pubmed publisher
	Kashat L, So A, Masui O, Wang X, Cao J, Meng X, et al. Secretome-based identification and characterization of potential biomarkers in thyroid cancer. J Proteome Res. 2010;9:5757-69 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nucleolin Monoclonal Antibody (ZN004)

Catalog # :

39-6400

Quantity :

100 ug

Price :

US 520.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: 0.1-1.0 ug/mL, Immunocytochemistry: 5-10 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human, Mouse

Clone :

ZN004

Isotype :

IgG2b, kappa

Storage :

-20 C

Description :

Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

Immunogen :

Synthetic peptide derived from the internal region of the human nucleolin protein

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-1.0 ug/mL, Immunocytochemistry: 5-10 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

B530004O11Rik; C23; D0Nds28; D1Nds28; FLJ45706; FLJ59041; Ncl; Nuc; Nucl; nucl antibody; Nucleolin; nucleolin-like protein; Protein C23

more info or order :

Invitrogen product webpage