TACR1 Monoclonal Antibody (ZN003) | Invitrogen 39-6100 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TACR1 Monoclonal Antibody (ZN003)

catalog :

39-6100

quantity :

100 µg

price :

US 430

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZN003

reactivity :

least shrew, human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; least shrew	Alkam T, Chebolu S, Darmani N. Cyclophosphamide causes activation of protein kinase A (PKA) in the brainstem of vomiting least shrews (Cryptotis parva). Eur J Pharmacol. 2014;722:156-64 pubmed
	Oliveira L, Oliveira M, Moriya H, Moreira T, Takakura A. Respiratory disturbances in a mouse model of Parkinson's disease. Exp Physiol. 2019;104:729-739 pubmed publisher
	Burmeister A, Johnson M, Chauhan V, Moerdyk Schauwecker M, Young A, Cooley I, et al. Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P. J Neuroinflammation. 2017;14:245 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TACR1 Monoclonal Antibody (ZN003)

Catalog # :

39-6100

Quantity :

100 µg

Price :

US 430

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Insect, Mouse, Rat

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Western Blot: 1 µg/mL

Species :

Human, Insect, Mouse, Rat

Clone :

ZN003

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.

Immunogen :

Synthetic peptide derived from an internal sequence of the human, mouse, and rat NK1 receptor proteins

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Western Blot: 1 µg/mL

Aliases :

neurokinin 1 receptor; neurokinin receptor 1; neurokinin receptor subtype NK1; neurokinin-1 receptor; Nk1 receptor; NK-1 receptor; Nk1r; NK-1R; NKIR; SPR; substance p receptor; substance-P receptor; TAC1R; tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1; truncated neurokinin-1 receptor

more info or order :

Invitrogen product webpage