TCL1A Monoclonal Antibody (1 21) | Invitrogen 39-4800 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCL1A Monoclonal Antibody (1 21)

catalog :

39-4800

quantity :

100 µg

price :

US 482

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1 21

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000	Alsagaby S, Khanna S, Hart K, Pratt G, Fegan C, Pepper C, et al. Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia. J Proteome Res. 2014;13:5051-62 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200; fig 1	Liu T, Chen S, Kuo S, Cheng A, Lin C. E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression of the memory B-cell-associated miR-223: possible correlation with stage and treatment response. Mod Pathol. 2010;23:1507-17 pubmed publisher
	Christensen H, Trotter C, Hickman M, Edmunds W. Re-evaluating cost effectiveness of universal meningitis vaccination (Bexsero) in England: modelling study. BMJ. 2014;349:g5725 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TCL1A Monoclonal Antibody (1 21)

Catalog # :

39-4800

Quantity :

100 µg

Price :

US 482

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Species :

Human

Clone :

1 21

Isotype :

IgG2b, kappa

Storage :

-20°C

Description :

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (summarized by Virgilio et al., 1998). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).

Immunogen :

Recombinant full-length human TCL-1A protein

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Aliases :

oncogene TCL1; Oncogene TCL-1; Protein p14 TCL1; T cell lymphoma breakpoint 1; T-cell leukemia/lymphoma 1A; T-cell leukemia/lymphoma protein 1A; T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein); T-cell lymphoma breakpoint 1; T-cell lymphoma-1; T-cell lymphoma-1A; TCL1; TCL-1; TCL1A