product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CDKN2C Monoclonal Antibody (ZP001)
catalog :
39-3400
quantity :
100 ug
price :
US 471.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ZP001
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry
more info or order :
Invitrogen product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3
Pozo K, Hillmann A, Augustyn A, Plattner F, Hai T, Singh T, et al. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget. 2015;6:12080-93 pubmed
  • western blot; rat; 1:500; fig 5
Toledano Y, Zonis S, Ren S, Wawrowsky K, Chesnokova V, Melmed S. Estradiol partially recapitulates murine pituitary cell cycle response to pregnancy. Endocrinology. 2012;153:5011-22 pubmed
  • western blot; mouse; 1:2000
Torchia E, Boyd K, Rehg J, Qu C, Baker S. EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice. Mol Cell Biol. 2007;27:7918-34 pubmed
Forget A, Ayrault O, den Besten W, Kuo M, Sherr C, Roussel M. Differential post-transcriptional regulation of two Ink4 proteins, p18 Ink4c and p19 Ink4d. Cell Cycle. 2008;7:3737-46 pubmed
product information
Product Type :
Antibody
Product Name :
CDKN2C Monoclonal Antibody (ZP001)
Catalog # :
39-3400
Quantity :
100 ug
Price :
US 471.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Mouse
Clone :
ZP001
Isotype :
IgG1, kappa
Storage :
-20 C
Description :
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Immunogen :
Recombinant, full-length mouse p18INK4c
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
Aliases :
C77269; CDK6 inhibitor p18; Cdkn2c; CDKN6; cyclin dependent kinase inhibitor 2C; cyclin-dependent inhibitor; cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase 6 inhibitor p18; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); INK4c; p18; p18INK4c; p18-INK4c; p18-INK6
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA