INCENP Monoclonal Antibody (58-217) | Invitrogen 39-2800 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

INCENP Monoclonal Antibody (58-217)

catalog :

39-2800

quantity :

100 µg

price :

US 580

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

58-217

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:150; loading ...; fig 3	Unruhe Knauf B, Knauer S. Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. Methods Mol Biol. 2017;1510:47-59 pubmed
immunocytochemistry; human	Vazquez Martin A, Sauri Nadal T, Menendez O, Oliveras Ferraros C, Cufí S, Corominas Faja B, et al. Ser2481-autophosphorylated mTOR colocalizes with chromosomal passenger proteins during mammalian cell cytokinesis. Cell Cycle. 2012;11:4211-21 pubmed publisher
western blot; human; 1:500; fig 4h	Cho H, Shimazu T, Toyokawa G, Daigo Y, Maehara Y, Hayami S, et al. Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun. 2012;3:1072 pubmed publisher
	Flashner S, Swift M, Sowash A, Fahmy A, Azizkhan Clifford J. Transcription factor Sp1 regulates mitotic chromosome assembly and segregation. Chromosoma. 2022;131:175-191 pubmed publisher
	Adriaans I, Hooikaas P, Aher A, Vromans M, van Es R, Grigoriev I, et al. MKLP2 Is a Motile Kinesin that Transports the Chromosomal Passenger Complex during Anaphase. Curr Biol. 2020;30:2628-2637.e9 pubmed publisher
	Renshaw M, Panagiotou T, Lavoie B, Wilde A. CDK11p58-cyclin L1β regulates abscission site assembly. J Biol Chem. 2019;294:18639-18649 pubmed publisher
	Hindriksen S, Bramer A, Truong M, Vromans M, Post J, Verlaan Klink I, et al. Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells. PLoS ONE. 2017;12:e0179514 pubmed publisher
	Vazquez Martin A, Oliveras Ferraros C, Menendez J. The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis. Cell Cycle. 2009;8:2385-98 pubmed

product information

Product Type :

Antibody

Product Name :

INCENP Monoclonal Antibody (58-217)

Catalog # :

39-2800

Quantity :

100 µg

Price :

US 580

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

58-217

Isotype :

IgG1

Storage :

-20°C

Description :

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.

Immunogen :

Recombinant human INCENP (inner centromere protein)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP

more info or order :

Invitrogen product webpage