VAV1 Monoclonal Antibody (ZV003) | Invitrogen 39-2050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

VAV1 Monoclonal Antibody (ZV003)

catalog :

39-2050

quantity :

500 µL

price :

375 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ZV003

reactivity :

human, mouse, chicken

application :

western blot, ELISA, immunocytochemistry, western blot knockout validation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; chicken; fig 1	Chen C, Martin V, Gorenstein N, Geahlen R, Post C. Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. Mol Cell Biol. 2011;31:2984-96 pubmed publisher
	Thomas A, Mariani Floderer C, LÃ³pez Huertas M, Gros N, Hamard PÃ©ron E, Favard C, et al. Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells. J Virol. 2015;89:8162-81 pubmed publisher

product information

Product Type :

Antibody

Product Name :

VAV1 Monoclonal Antibody (ZV003)

Catalog # :

39-2050

Quantity :

500 µL

Price :

375 USD

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay Dependent, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:100-1:1000

Species :

Human, Mouse

Clone :

ZV003

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Immunogen :

Synthetic peptide derived from an internal region of the human, mouse and rat Vav1 proteins

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:100-1:1000

Aliases :

oncogene vav; p95; p95vav; Proto-oncogene vav; VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav guanine nucleotide exchange factor 1; vav oncogene; vav proto-oncogene; VAV1; vav-T