This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Parkin Monoclonal Antibody (PRK109)
catalog :
39-0900
quantity :
100 ug
price :
US 471.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PRK109
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 3
Reference
Wu R, Xu F, Li J, Wang F, Chen N, Wang X, et al. Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1. iScience. 2024;27:108982 pubmed publisher
Cadile F, Recchia D, Ansaldo M, Rossi P, Rastelli G, Boncompagni S, et al. Diaphragm Fatigue in SMNΔ7 Mice and Its Molecular Determinants: An Underestimated Issue. Int J Mol Sci. 2023;24: pubmed publisher
Pawlyk A, Giasson B, Sampathu D, Perez F, Lim K, Dawson V, et al. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J Biol Chem. 2003;278:48120-8 pubmed
product information
Product Type :
Antibody
Product Name :
Parkin Monoclonal Antibody (PRK109)
Catalog # :
39-0900
Quantity :
100 ug
Price :
US 471.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500
Species :
Human, Mouse, Rat
Clone :
PRK109
Isotype :
IgG1, kappa
Storage :
-20 C
Description :
The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Immunogen :
Full length recombinant human Parkin
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500
Aliases :
AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA