Aurora C Polyclonal Antibody | Invitrogen 38-9400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Aurora C Polyclonal Antibody

catalog :

38-9400

quantity :

100 ug

price :

US 520.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; fig 1 western blot; human; fig 1	Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Aurora C Polyclonal Antibody

Catalog # :

38-9400

Quantity :

100 ug

Price :

US 520.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 2-3 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C

Description :

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.

Immunogen :

Synthetic peptide derived from an internal region of the human Aurora C (Serine/threonine-protein kinase 13, Serine/threonine kinase AIE2, Aurora/IPL1/Eg2 protein 2, Aurora/IPL1-related kinase 3) protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-3 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

AIE1; AIE2; AIK3; AIRK3; ARK3; ARK-3; AurC; AURKC; Aurora 3; aurora B; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; aurora-C; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; SPGF5; STK13

more info or order :

Invitrogen product webpage