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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Claudin 12 Polyclonal Antibody
catalog :
38-8200
quantity :
100 µg
price :
US 430
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
domestic goat, human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; domestic goat; 1:1000; fig 3
Elfers K, Marr I, Wilkens M, Breves G, Langeheine M, Brehm R, et al. Expression of Tight Junction Proteins and Cadherin 17 in the Small Intestine of Young Goats Offered a Reduced N and/or Ca Diet. PLoS ONE. 2016;11:e0154311 pubmed publisher
  • western blot; mouse; fig 3
Kühne H, Hause G, Grundmann S, Schutkowski A, Brandsch C, Stangl G. Vitamin D receptor knockout mice exhibit elongated intestinal microvilli and increased ezrin expression. Nutr Res. 2016;36:184-92 pubmed publisher
El Chami C, Foster A, Johnson C, Clausen R, Cornwell P, Haslam I, et al. Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes. Br J Dermatol. 2021;184:482-494 pubmed publisher
Casselbrant A, F ndriks L, Wallenius V. Glycocholic acid and butyrate synergistically increase vitamin D-induced calcium uptake in Caco-2 intestinal epithelial cell monolayers. Bone Rep. 2020;13:100294 pubmed publisher
Markov A, Fedorova A, Kravtsova V, Bikmurzina A, Okorokova L, Matchkov V, et al. Circulating Ouabain Modulates Expression of Claudins in Rat Intestine and Cerebral Blood Vessels. Int J Mol Sci. 2020;21: pubmed publisher
Castro Dias M, Coisne C, Baden P, Enzmann G, Garrett L, Becker L, et al. Claudin-12 is not required for blood-brain barrier tight junction function. Fluids Barriers CNS. 2019;16:30 pubmed publisher
Chen H, Lu R, Zhang Y, Sun J. Vitamin D Receptor Deletion Leads to the Destruction of Tight and Adherens Junctions in Lungs. Tissue Barriers. 2018;6:1-13 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Claudin 12 Polyclonal Antibody
Catalog # :
38-8200
Quantity :
100 µg
Price :
US 430
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:100-1:500, Western Blot: 1-3 µg/mL
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands.
Immunogen :
Synthetic peptide derived from the N-terminal region of mouse and human Claudin-12
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:500, Western Blot: 1-3 µg/mL
Aliases :
claudin 12; claudin-12; Cldn12; RGD1561053
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA