BMPR1A Polyclonal Antibody | Invitrogen 38-6000 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BMPR1A Polyclonal Antibody

catalog :

38-6000

quantity :

100 µg

price :

US 430

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:200; loading ...; fig 4c western blot; mouse; 1:200; loading ...; fig 4a	Liu P, Jiang B, Ma J, Lin P, Zhang Y, Shao C, et al. S113R mutation in SLC33A1 leads to neurodegeneration and augmented BMP signaling in a mouse model. Dis Model Mech. 2017;10:53-62 pubmed publisher
	Nyamsuren G, Rapp G, Dihazi H, Zeisberg E, Tampe D, Tampe B, et al. PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation. Sci Rep. 2021;11:24075 pubmed publisher
	Al Dalahmah O, Campos Soares L, Nicholson J, Draijer S, Mundim M, Lu V, et al. Galectin-3 modulates postnatal subventricular zone gliogenesis. Glia. 2020;68:435-450 pubmed publisher
	Russell B, Rigueur D, Weaver K, Sund K, Basil J, Hufnagel R, et al. Homozygous missense variant in BMPR1A resulting in BMPR signaling disruption and syndromic features. Mol Genet Genomic Med. 2019;7:e969 pubmed publisher
	Guo Y, Yuan Y, Wu L, Ho T, Jing J, Sugii H, et al. BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair. Bone Res. 2018;6:30 pubmed publisher
	Townsend K, Madden C, Blaszkiewicz M, McDougall L, Tupone D, Lynes M, et al. Reestablishment of Energy Balance in a Male Mouse Model With POMC Neuron Deletion of BMPR1A. Endocrinology. 2017;158:4233-4245 pubmed publisher

product information

Product Type :

Antibody

Product Name :

BMPR1A Polyclonal Antibody

Catalog # :

38-6000

Quantity :

100 µg

Price :

US 430

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser/thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Immunogen :

Synthetic peptide derived from an internal region of the human BMPR-1A (bone morphogenetic protein receptor type 1A, Serine/threonine protein kinase receptor R5 (SKR5), activin receptor-like kinase-3 (ALK-3)), which differs from mouse and rat BMPR-1A by one nonconservative amino acid replacement.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 2 µg/mL

Aliases :

10q23del; 1110037I22Rik; activin A receptor, type II-like kinase 3; activin receptor-like kinase 3; ACVRLK3; ALK3; ALK-3; AU045487; BMP type-1A receptor; BMP-2/BMP-4 receptor; Bmpr; Bmpr1a; BMPR-1A; BMPRIA; BMPR-IA; Bone morphogenetic protein 4 receptor; bone morphogenetic protein receptor type 1A; bone morphogenetic protein receptor type IA; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type 1A; bone morphogenetic protein receptor, type IA; CD292; Serine/threonine-protein kinase receptor R5; SKR5

more info or order :

Invitrogen product webpage