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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PITX3 Polyclonal Antibody
catalog :
38-2850
quantity :
50 µg
price :
US 420.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:250; fig 5
Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, et al. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Dev Biol. 2016;409:55-71 pubmed publisher
Schmidt S, Luecken M, Tr xfc mbach D, Hembach S, Niedermeier K, Wenck N, et al. Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease. Nat Commun. 2022;13:4819 pubmed publisher
Nouri P, Götz S, Rauser B, Irmler M, Peng C, Trumbach D, et al. Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling. Front Cell Dev Biol. 2020;8:587778 pubmed publisher
Kim H, Park H, Choi H, Chang Y, Park H, Shin J, et al. Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids. Stem Cell Reports. 2019;: pubmed publisher
Jovanovic V, Salti A, Tilleman H, Zega K, Jukic M, Zou H, et al. BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells. J Neurosci. 2018;38:1662-1676 pubmed publisher
Nouri N, Awatramani R. A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons. Development. 2017;144:916-927 pubmed publisher
Gazea M, Tasouri E, Heigl T, Bosch V, Tucker K, Blaess S. Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis. Neurogenesis (Austin). 2016;3:e1248206 pubmed publisher
Villaescusa J, Li B, Toledo E, Rivetti di Val Cervo P, Yang S, Stott S, et al. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease. EMBO J. 2016;35:1963-78 pubmed publisher
Jiang H, Xu Z, Zhong P, Ren Y, Liang G, Schilling H, et al. Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons. Nat Commun. 2015;6:10100 pubmed publisher
Fukusumi Y, Meier F, Götz S, Matheus F, Irmler M, Beckervordersandforth R, et al. Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse. J Neurosci. 2015;35:13385-401 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PITX3 Polyclonal Antibody
Catalog # :
38-2850
Quantity :
50 µg
Price :
US 420.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Mouse
Applications :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent
Species :
Mouse
Isotype :
IgG
Storage :
-20°C
Description :
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
Immunogen :
Synthetic peptide derived from the N-terminal region of the mouse PiTX3 protein.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent
Aliases :
ak; aphakia; ASMD; ASOD; CTPP4; CTRCT11; Homeobox protein PITX3; homeobox protein PTX3; MGC12766; paired like homeodomain 3; paired-like homeodomain 3; paired-like homeodomain transcription factor 3; Pituitary homeobox 3; Pituitary homeobox 3 (Homeobox protein PITX3); PITX3; Ptx3
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA