HSP90 beta Monoclonal Antibody (H9010) | Invitrogen 37-9400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSP90 beta Monoclonal Antibody (H9010)

catalog :

37-9400

quantity :

1 mL

price :

US 500.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

H9010

reactivity :

human, mouse, rat, chicken, domestic rabbit

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; loading ...; fig 6b immunocytochemistry; human; loading ...; fig 6a western blot; human; loading ...; fig 6b	Jeong J, Choi J, Kim W, Dann P, Takyar F, Gefter J, et al. Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells. J Biol Chem. 2019;294:887-901 pubmed publisher
immunoprecipitation; human; loading ...; fig 4f immunocytochemistry; human; loading ...; fig 4g western blot; human; loading ...; fig 4f	Jeong J, Kim W, Kim L, VanHouten J, Wysolmerski J. HER2 signaling regulates HER2 localization and membrane retention. PLoS ONE. 2017;12:e0174849 pubmed publisher
immunocytochemistry; human; fig 5 western blot; human; fig 5	Jeong J, VanHouten J, Dann P, Kim W, Sullivan C, Yu H, et al. PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proc Natl Acad Sci U S A. 2016;113:E282-90 pubmed publisher
immunocytochemistry; mouse western blot; mouse	Shi C, Huang X, Zhang B, Zhu D, Luo H, Lu Q, et al. The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein. PLoS ONE. 2015;10:e0138936 pubmed publisher
western blot; mouse; 0.1 ug/ml	Riebold M, Kozany C, Freiburger L, Sattler M, Buchfelder M, Hausch F, et al. A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. Nat Med. 2015;21:276-80 pubmed publisher
immunocytochemistry; human western blot; human	Xiong X, Wang Y, Liu C, Lu Q, Liu T, Chen G, et al. Heat shock protein 90? stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells. Exp Cell Res. 2014;326:78-89 pubmed publisher
immunocytochemistry; rat; 1:50	Vanhecke D, Bellmann R, Baum O, Graber W, Eggli P, Keller H, et al. Pseudovacuoles--immobilized by high-pressure freezing--are associated with blebbing in walker carcinosarcoma cells. J Microsc. 2008;230:253-62 pubmed publisher
	Malkin E, De Michino S, Lambie M, Gill R, Zhao Z, Rostami A, et al. Cell-free DNA topology depends on its subcellular and cellular origins in cancer. JCI Insight. 2022;7: pubmed publisher
	Song Q, Wen J, Li W, Xue J, Zhang Y, Liu H, et al. HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination. Cancer Sci. 2022;113:1463-1474 pubmed publisher
	Jeong J, Shin J, Li W, Hong J, Lim J, Hwang J, et al. MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells. Cell Rep. 2021;37:110160 pubmed publisher
	Lee Y, Fong S, Shon J, Zhang S, Brooks R, Lahens N, et al. Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle. Sci Adv. 2021;7: pubmed publisher
	Camacho Ben xed tez A, Vasconcellos R, Lombide P, Viotti H, P xe9 rez W, Cazales N, et al. Heat shock protein HSP90 immunoexpression in equine endometrium during oestrus, dioestrus and anoestrus. Anat Histol Embryol. 2021;50:50-57 pubmed publisher
	Chan Z, Deng L, Lee C. Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover. Eneuro. 2020;7: pubmed publisher
	Jones L, Kumar S, Bell C, Peoples V, Crenshaw B, Coats M, et al. Effects of Pseudomonas aeruginosa on Microglial-Derived Extracellular Vesicle Biogenesis and Composition. Pathogens. 2019;8: pubmed publisher
	Qin E, Cooper D, Abbott K, Lennon J, Nagaraja S, Mackay A, et al. Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma. Cell. 2017;170:845-859.e19 pubmed publisher
	Hall J, Seedarala S, Zhao H, Garg G, Ghosh S, Blagg B. Novobiocin Analogues That Inhibit the MAPK Pathway. J Med Chem. 2016;59:925-33 pubmed publisher
	Greer C, Tanaka Y, Kim Y, Xie P, Zhang M, Park I, et al. Histone Deacetylases Positively Regulate Transcription through the Elongation Machinery. Cell Rep. 2015;13:1444-1455 pubmed publisher
	Palii S, Cui Y, Innes C, Paules R. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit. Cell Cycle. 2013;12:1105-18 pubmed publisher
	Echeverria P, Bernthaler A, Dupuis P, Mayer B, Picard D. An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine. PLoS ONE. 2011;6:e26044 pubmed publisher
	Smith L, Qutob O, Watson M, Beavis A, Potts D, Welham K, et al. Proteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome?. Neoplasia. 2009;11:1194-207 pubmed
	Luo S, Zhang B, Dong X, Tao Y, Ting A, Zhou Z, et al. HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance. Neuron. 2008;60:97-110 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HSP90 beta Monoclonal Antibody (H9010)

Catalog # :

37-9400

Quantity :

1 mL

Price :

US 500.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Chicken, Human, Mouse, Rabbit

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Chicken, Human, Mouse, Rabbit

Clone :

H9010

Isotype :

IgG2a, kappa

Storage :

-20°C

Description :

Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and some kinases.

Immunogen :

Recombinant human HSP90-beta

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)

more info or order :

Invitrogen product webpage