Connexin 40 Monoclonal Antibody (2F9A11) | Invitrogen 37-8900 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Connexin 40 Monoclonal Antibody (2F9A11)

catalog :

37-8900

quantity :

100 µg

price :

US 450

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F9A11

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; rat immunocytochemistry; mouse	Bautista W, Rash J, Vanderpool K, Yasumura T, Nagy J. Re-evaluation of connexins associated with motoneurons in rodent spinal cord, sexually dimorphic motor nuclei and trigeminal motor nucleus. Eur J Neurosci. 2014;39:757-70 pubmed publisher
immunohistochemistry; mouse; 1:200; fig 4	Boittin F, Alonso F, Le Gal L, Allagnat F, Beny J, Haefliger J. Connexins and M3 muscarinic receptors contribute to heterogeneous Ca(2+) signaling in mouse aortic endothelium. Cell Physiol Biochem. 2013;31:166-78 pubmed publisher
immunoprecipitation; rat; fig 5 immunocytochemistry; rat; 1:250; fig 5 western blot; rat; 1:250; fig 5	Halidi N, Alonso F, Burt J, Beny J, Haefliger J, Meister J. Intercellular calcium waves in primary cultured rat mesenteric smooth muscle cells are mediated by connexin43. Cell Commun Adhes. 2012;19:25-37 pubmed publisher
immunohistochemistry; mouse; 1:200; fig 5	Alonso F, Boittin F, Beny J, Haefliger J. Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta. Am J Physiol Heart Circ Physiol. 2010;299:H1365-73 pubmed publisher
	He Y, Tacconi C, Dieterich L, Kim J, Restivo G, Gousopoulos E, et al. Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic Profiling. Cells. 2022;11: pubmed publisher
	Liang D, Xue J, Geng L, Zhou L, Lv B, Zeng Q, et al. Cellular and molecular landscape of mammalian sinoatrial node revealed by single-cell RNA sequencing. Nat Commun. 2021;12:287 pubmed publisher
	Lee J, Sutani A, Kaneko R, Takeuchi J, Sasano T, Kohda T, et al. In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix. Nat Commun. 2020;11:4283 pubmed publisher
	Dai W, Nadadur R, Brennan J, Smith H, Shen K, Gadek M, et al. ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circ Res. 2020;127:e28-e43 pubmed publisher
	Islam M, Steward R. Probing Endothelial Cell Mechanics Through Connexin 43 Disruption. Exp Mech. 2019;59:327-336 pubmed publisher
	Baron C, Kester L, Klaus A, Boisset J, Thambyrajah R, Yvernogeau L, et al. Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta. Nat Commun. 2018;9:2517 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Connexin 40 Monoclonal Antibody (2F9A11)

Catalog # :

37-8900

Quantity :

100 µg

Price :

US 450

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay-dependent

Species :

Human, Mouse

Clone :

2F9A11

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Connexin 40 (Cx40), belongs to the connexin family of gap junction proteins, which are expressed in pancreas, kidney, skeletal muscle, liver, placenta and heart. Connexin 40 is highly expressed in vascular endothelial cells, and the mammalian heart (specifically in the atrial myocardium, and the His-Purkinje conduction system). At least three other connexins are expressed in the heart, including Cx37 (endocardium), Cx43 (atrial and ventricular myocardium, and distal parts of the conduction system) and Cx45 (throughout the heart). Cx40 and Cx43 frequently co-localize in cells of the cardiovascular system and participate in the formation of heterotypic gap junction channels.

Immunogen :

Synthetic peptide corresponding to the C-terminus of mouse Connexin40

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: Assay-dependent

Aliases :

5730555N10Rik; ATFB11; Cnx40; connexin 40; connexin-40; Cx40; Cxn-40; Gap junction alpha-5 protein; gap junction membrane channel protein alpha 5; gap junction protein; gap junction protein alpha 5; gap junction protein alpha 5 40kDa; gap junction protein, alpha 5; GJA5; Gja-5

more info or order :

Invitrogen product webpage