p19 INK4d Monoclonal Antibody (2D2G4) | Invitrogen 37-8700 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

p19 INK4d Monoclonal Antibody (2D2G4)

catalog :

37-8700

quantity :

100 µg

price :

US 400

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D2G4

reactivity :

human, mouse

application :

western blot, ELISA, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human	Sonzogni S, Ogara M, Castillo D, Sirkin P, Radicella J, CÃ¡nepa E. Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation. Mol Cell Biochem. 2015;398:63-72 pubmed publisher
western blot; mouse	Sonzogni S, Ogara M, Belluscio L, Castillo D, Scassa M, Cánepa E. p19INK4d is involved in the cellular senescence mechanism contributing to heterochromatin formation. Biochim Biophys Acta. 2014;1840:2171-83 pubmed publisher
	Koyama M, Matsuzaki Y, Yogosawa S, Hitomi T, Kawanaka M, Sakai T. ZD1839 induces p15INK4b and causes G1 arrest by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway. Mol Cancer Ther. 2007;6:1579-87 pubmed

product information

Product Type :

Antibody

Product Name :

p19 INK4d Monoclonal Antibody (2D2G4)

Catalog # :

37-8700

Quantity :

100 µg

Price :

US 400

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Clone :

2D2G4

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.

Immunogen :

A recombinant full length human p19 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

CDK inhibitor p19INK4d; CDK4I; CDKN2D; cell cycle inhibitor, Nur77 associating protein; cyclin dependent kinase inhibitor 2D; cyclin-dependent kinase 4 inhibitor D; cyclin-dependent kinase 4 inhibitor D p19; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; INK4d; MTS1; p16-INK4; p16-INK4a; p19; p19INK4d; p19-INK4D; similar to cyclin-dependent kinase inhibitor 2D

more info or order :

Invitrogen product webpage