Ephrin B1 Monoclonal Antibody (2D3E9) | Invitrogen 37-8100 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ephrin B1 Monoclonal Antibody (2D3E9)

catalog :

37-8100

quantity :

100 µg

price :

US 450

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D3E9

reactivity :

human, mouse, rat, chicken

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 2 ug/ml; loading ...; tbl 1	Burch A, Tao Cheng J, Dosemeci A. A novel synaptic junction preparation for the identification and characterization of cleft proteins. PLoS ONE. 2017;12:e0174895 pubmed publisher
western blot; mouse; 1:1000; fig 1	Hruska M, Henderson N, Xia N, Le Marchand S, Dalva M. Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3. Nat Neurosci. 2015;18:1594-605 pubmed publisher
	Vreeken D, Bruikman C, Cox S, Zhang H, Lalai R, Koudijs A, et al. EPH receptor B2 stimulates human monocyte adhesion and migration independently of its EphrinB ligands. J Leukoc Biol. 2020;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Ephrin B1 Monoclonal Antibody (2D3E9)

Catalog # :

37-8100

Quantity :

100 µg

Price :

US 450

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Chicken, Human

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Species :

Chicken, Human

Clone :

2D3E9

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Immunogen :

Synthetic peptide derived from the ephrin-B sequence.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 2 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent

Aliases :

CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFNB1; EFNB3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; ephrin B1; Ephrin B3; EphrinB1; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B1 precursor; Epl2; EPLG2; EPLG8; kinase ephrin-B1; Lerk2; LERK-2; LERK8; Stimulated by retinoic acid gene 1 protein; Stra1; STRA1 protein; transmembrane ligand

more info or order :

Invitrogen product webpage