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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
nNOS Monoclonal Antibody (3G6B10)
catalog :
37-2800
quantity :
100 µg
price :
US 430.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3G6B10
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:500; loading ...; fig 5
Robison C, McHenry J, Hull E. Increased expression of carbon monoxide-producing enzymes in the MPOA after sexual experience in male rats. Physiol Behav. 2017;171:149-157 pubmed publisher
  • western blot; mouse; loading ...; fig 7b
Dolunay A, Senol S, Temiz Resitoglu M, Guden D, Sari A, Sahan Firat S, et al. Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-?B, Caspase-1/11, ASC, NOX, and NOS Isoforms. Inflammation. 2017;40:366-386 pubmed publisher
  • immunohistochemistry; rat; 1:1,000
Barbaresi P, Mensà E, Lariccia V, Desiato G, Fabri M, Gratteri S. Intracallosal neuronal nitric oxide synthase neurons colocalize with neurokinin 1 substance P receptor in the rat. J Comp Neurol. 2015;523:589-607 pubmed publisher
  • immunocytochemistry; human; 1:250
Elíes J, Dallas M, Boyle J, Scragg J, Duke A, Steele D, et al. Inhibition of the cardiac Na? channel Nav1.5 by carbon monoxide. J Biol Chem. 2014;289:16421-9 pubmed publisher
  • western blot; rat; 1:500; fig 1
Barbaresi P, Mensà E, Lariccia V, Pugnaloni A, Amoroso S, Fabri M. Differential distribution of parvalbumin- and calbindin-D28K-immunoreactive neurons in the rat periaqueductal gray matter and their colocalization with enzymes producing nitric oxide. Brain Res Bull. 2013;99:48-62 pubmed publisher
  • western blot; rat; fig 5
Kraner S, Novak K, Wang Q, Peng J, Rich M. Altered sodium channel-protein associations in critical illness myopathy. Skelet Muscle. 2012;2:17 pubmed publisher
  • western blot; rat; fig 4
Gökçek Saraç Ç, Karakurt S, Adali O, Jakubowska Doğru E. Correlation between hippocampal levels of neural, epithelial and inducible NOS and spatial learning skills in rats. Behav Brain Res. 2012;235:326-33 pubmed publisher
  • western blot; rat; fig 2
Barbaresi P, Quaranta A, Amoroso S, Mensà E, Fabri M. Immunocytochemical localization of calretinin-containing neurons in the rat periaqueductal gray and colocalization with enzymes producing nitric oxide: a double, double-labeling study. Synapse. 2012;66:291-307 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Aguirre E, López Bernardo E, Cadenas S. Functional evidence for nitric oxide production by skeletal-muscle mitochondria from lipopolysaccharide-treated mice. Mitochondrion. 2012;12:126-31 pubmed publisher
J xe4 nsch M, Lubomirov L, Trum M, Williams T, Schmitt J, Schuh K, et al. Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice. FEBS Open Bio. 2023;13:118-132 pubmed publisher
Wind M, Tsakiridis A. In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells. Curr Protoc. 2021;1:e244 pubmed publisher
Wind M, Gogolou A, Manipur I, Granata I, Butler L, Andrews P, et al. Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives. Development. 2021;148: pubmed publisher
Jiménez Altayó F, Ortiz Romero P, Puertas Umbert L, Dantas A, Perez B, Vila E, et al. Stenosis coexists with compromised α1-adrenergic contractions in the ascending aorta of a mouse model of Williams-Beuren syndrome. Sci Rep. 2020;10:889 pubmed publisher
Gulisano W, Melone M, Ripoli C, Rosaria Tropea M, Li Puma D, Giunta S, et al. Neuromodulatory action of picomolar extracellular Aβ42 oligomers on pre- and postsynaptic mechanisms underlying synaptic function and memory. J Neurosci. 2019;: pubmed publisher
Chen L, Zhang J, Suo H, Wang W, Wang H, Zhang Y, et al. Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice. Foods. 2019;8: pubmed publisher
Bastian C, Zaleski J, Stahon K, Parr B, McCray A, Day J, et al. NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. J Neurosci. 2018;38:6247-6266 pubmed publisher
Dial A, Rooprai P, Lally J, Bujak A, Steinberg G, Ljubicic V. The role of AMP-activated protein kinase in the expression of the dystrophin-associated protein complex in skeletal muscle. FASEB J. 2018;32:2950-2965 pubmed publisher
Sullivan J, Pardieck J, Hyndman K, Pollock J. Renal NOS activity, expression, and localization in male and female spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2010;298:R61-9 pubmed publisher
Sessa W. The nitric oxide synthase family of proteins. J Vasc Res. 1994;31:131-43 pubmed
product information
Product Type :
Antibody
Product Name :
nNOS Monoclonal Antibody (3G6B10)
Catalog # :
37-2800
Quantity :
100 µg
Price :
US 430.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Mouse, Rat
Clone :
3G6B10
Isotype :
IgG1, kappa
Storage :
-20°C
Description :
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.
Immunogen :
Recombinant protein derived from the N-terminal region of rat nNOS protein.
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
Aliases :
2310005C01Rik; bNOS; bNOS1; Brain NOS; Constitutive NOS; IHPS1; NC-NOS; neuronal nitric oxide synthase; neuronal nitric oxide synthase NOS1; neuronal NOS; nitric oxidase synthase; nitric oxide synthase; nitric oxide synthase 1; nitric oxide synthase 1 (neuronal); nitric oxide synthase 1, neuronal; nitric oxide synthase, brain; nNOS; N-NOS; nNOS; NOS type I; NO; NOS; NOS Type 1; NOS type I; Nos1; Nos-1; NOS-I; Peptidyl-cysteine S-nitrosylase NOS1; Phospho-bNOS; Phospho-Brain NOS
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA