EphB2 Monoclonal Antibody (1A6C9) | Invitrogen 37-1700 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EphB2 Monoclonal Antibody (1A6C9)

catalog :

37-1700

quantity :

100 ug

price :

US 520.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1A6C9

reactivity :

human, chicken, Xenopus laevis

application :

western blot, ELISA, immunoprecipitation, proximity ligation assay, western blot knockout validation

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; loading ...; fig s6b	Enderle L, Shalaby K, Gorelik M, Weiss A, Blazer L, Paduch M, et al. A T cell redirection platform for co-targeting dual antigens on solid tumors. MAbs. 2021;13:1933690 pubmed publisher
proximity ligation assay; Xenopus laevis; 1:100; loading ...; fig 3e	Koppers M, Cagnetta R, Shigeoka T, Wunderlich L, Vallejo Ramirez P, Qiaojin Lin J, et al. Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. elife. 2019;8: pubmed publisher
immunoprecipitation; human; fig 4	Dubois F, Leroy C, Simon V, Benistant C, Roche S. YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells. Am J Cancer Res. 2015;5:1972-87 pubmed
western blot; human	Eriksson O, RamstrÃ¶m M, HÃ¶rnaeus K, Bergquist J, Mokhtari D, Siegbahn A. The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa. J Biol Chem. 2014;289:32379-91 pubmed publisher
western blot; human; 1:250; fig 6	Dai J, Buhusi M, Demyanenko G, Brennaman L, Hruska M, Dalva M, et al. Neuron glia-related cell adhesion molecule (NrCAM) promotes topographic retinocollicular mapping. PLoS ONE. 2013;8:e73000 pubmed publisher
	Bodin R, Paill xe9 V, Oullier T, Durand T, Aubert P, Le Berre Scoul C, et al. The ephrin receptor EphB2 regulates the connectivity and activity of enteric neurons. J Biol Chem. 2021;297:101300 pubmed publisher
	Washburn H, Xia N, Zhou W, Mao Y, Dalva M. Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility. Nat Commun. 2020;11:570 pubmed publisher
	Wu Z, Ashlin T, Xu Q, Wilkinson D. Role of forward and reverse signaling in Eph receptor and ephrin mediated cell segregation. Exp Cell Res. 2019;381:57-65 pubmed publisher
	Okumura F, Joo Okumura A, Obara K, Petersen A, Nishikimi A, Fukui Y, et al. Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2. Mol Biol Cell. 2017;28:3532-3541 pubmed publisher
	Richter M, Murai K, Bourgin C, Pak D, Pasquale E. The EphA4 receptor regulates neuronal morphology through SPAR-mediated inactivation of Rap GTPases. J Neurosci. 2007;27:14205-15 pubmed

product information

Product Type :

Antibody

Product Name :

EphB2 Monoclonal Antibody (1A6C9)

Catalog # :

37-1700

Quantity :

100 ug

Price :

US 520.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Chicken, Human

Applications :

ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500

Species :

Chicken, Human

Clone :

1A6C9

Isotype :

IgG1, kappa

Storage :

-20 C

Description :

EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

Immunogen :

A synthetic peptide derived from the C-terminal region of the recombinant EphB2 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:500

Aliases :

CAPB; cEK5; chicken embryo kinase 5; chicken embryo kinase 5 protein; developmentally-regulated Eph-related tyrosine kinase; DRT; EFL6; EFNB3; EK5; ELK; ELK-related tyrosine kinase; embryo kinase 5 protein CEK5; EPH B2; EPH receptor B2; eph tyrosine kinase 3; EPHB2; EphB2/CTF1; EphB2/CTF2; EPHB3; EPH-like kinase 5; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; Ephrin type-B receptor 2; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPHT3; EPLG8; EPTH3; ERK; ETECK; ETK2; HEK2; Hek5; HEK-6; LERK8; MGC87492; NET; Neural kinase; Nuk; Nuk receptor tyrosine kinase; PCBC; Prkm5; protein-tyrosine kinase HEK5; Qek5; Renal carcinoma antigen NY-REN-47; RGD1564232; Sek3; TYRO5; TYRO6; Tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase TYRO5

more info or order :

Invitrogen product webpage